Compare Dilaudid vs. Acetaminophen with codeine
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats moderate to severe pain.
Dilaudid (hydromorphone) is a powerful pain reliever that has significant risks for abuse and overdose.
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4.1/ 5 average rating with 51 reviewsforDilaudid
Treats mild to moderate pain.
Acetaminophen with codeine (acetaminophen / codeine) is a good option to treat pain when over-the-counter medicines aren't enough, but don't take too much acetaminophen (Tylenol) since it can hurt your liver.
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3.7/ 5 average rating with 581 reviewsforAcetaminophen with codeine
Upsides
- Dilaudid (hydromorphone) works better and faster at relieving pain than morphine.
- Available in a cheap generic version.
- Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
- Provides quick relief for mild to moderate pain.
- Good for as-needed pain and control.
- Generally well tolerated, especially if taken with food to lower risk of stomach upset.
- Lower rates of misuse compared to pure opioid medicines.
Downsides
- Constipation is a common side effect of Dilaudid (hydromorphone) and may require the use of laxatives or stool softeners.
- Dilaudid (hydromorphone) is fatal when combined with alcohol, muscle relaxants, and other medications that slow breathing.
- Long-term use of opioids will cause physical dependence.
- Dizziness and drowsiness is common, but your body may adjust.
- Many people get constipated taking Acetaminophen with codeine (acetaminophen / codeine).
- All opioid containing medicines have the risk of addiction and withdrawal when used long-term.
- Acetaminophen (Tylenol) has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful since many over-the-counter medicines also have acetaminophen.
Used for
- Pain management
Dosage forms
- Pill
- Extended release pill
- Liquid
- Suppository
- Pill
- Liquid
Price
Lowest price
$71.74
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$8.14
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Reviews
51 reviews so far
78%
saidit'sworth it
65%
saiditworked well
10%
saidit'sa big hassle
Have you used Dilaudid (hydromorphone)?
Leave a review581 reviews so far
69%
saidit'sworth it
41%
saiditworked well
9%
saidit'sa big hassle
Have you used Acetaminophen with codeine (acetaminophen / codeine)?
Leave a reviewSide effects
The Dilaudid (hydromorphone) FDA package insert doesn’t have numbers about how common side effects are.
The Acetaminophen with codeine (acetaminophen / codeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Slowed breathing
- Current use of medicine that affects liver enzyme CYP 3A4
- Age 65 or greater
- Higher doses
- Drinking alcohol
- Use with benzodiazepines
- Death from overdose
- Children age 18 and younger
- Death of newborn babies from opioid withdrawal
- Long-term use during pregnancy
- Tolerance, dependence, and addiction
- Taking more than the prescribed dose
- Long-term use
- History of drug abuse
- Driving impairment
- Taking Dilaudid (hydromorphone) with alcohol
- Taking other medicines that make you less alert
- Age 65 or greater
- Liver failure and death
- Alcohol use
- Taking over-the-counter medicines with acetaminophen
- History of liver disease
- High risk to children
- Use with other CNS depressants
- Use with alcohol
- Use with benzodiazepines
- Use with other opiates
- Severe allergic reaction