Compare doxepin vs. Butisol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT

doxepin

Prescription only

Butisol (butabarbital)

Prescription only
Treats depression and anxiety.

doxepin can treat depression and anxiety, but it's not a first choice medication because of its many side effects.

Helps you fall asleep.

Butisol (butabarbital) is not very good for sleeping problems because it can be addictive.

Upsides
  • doxepin has been consistently shown to improve symptoms of depression and anxiety.
  • doxepin has been used to treat depression for over forty years.
  • Butisol (butabarbital) works very quickly to help you fall asleep, within 45-60 minutes, and it lasts 6-8 hours.
Downsides
  • doxepin can make you very sleepy. Try taking it at bedtime if you need to be alert during the day.
  • You shouldn't drink alcohol with doxepin. It can worsen side effects like drowsiness.
  • You have to take it daily, especially if you are feeling better, for the medicine to do its job.
  • It can have more side effects than other antidepressants, like weight gain and increased appetite, decreased libido, and sleepiness.
  • It's not unusual for people to try different antidepressants until they find one that works for them.
  • Your body can get used to needing Butisol (butabarbital) for sleeping.
  • Butisol (butabarbital) can interact with a lot of medicines, vitamins and supplements.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
The doxepin FDA package insert doesn’t have numbers about how common side effects are.
1possible side effects
  • Sleepiness
    3%
See more detailed side effects
Risks and risk factors
  • Suicidal thoughts or behavior
    • Age 24 years or under
  • Unmasking of bipolar disorder
    • Bipolar disorder
  • Serotonin syndrome
    • Taking MAOIs (monoamine oxidase inhibitors)
  • Heart problems
    • History of heart disease
    • Adults over 65
    • Electrolyte imbalance
  • Sleepiness
    • Adults 65 years or older
    • Taking other medicines that cause drowsiness (antihistamines, sleep medications, narcotic pain medications)
    • Alcohol
  • Dizziness and falls
    • Age 65 years or older
See more detailed risks and warnings
  • Addiction and tolerance
  • Behavior changes
  • Feeling awake
    • Having acute or chronic pain
    • age 65 or older
  • Breathing problems
    • Drinking alcohol
    • Taking narcotics, tranquilizers or antihistamines
See more detailed risks and warnings