Compare Doxepin vs. Dalmane

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Zonalon (Doxepin)

Prescription only

Dalmane (flurazepam)

Prescription only
Helps you stop itching.

Zonalon (Doxepin) works well treating itchy skin, but could make you sleepy.

Helps you fall asleep.

Dalmane (flurazepam) helps you fall asleep, but its effect can carry over to the next day and be addictive.

Upsides
  • In clinical trials, Zonalon (Doxepin) was found to be the most effective cream for treating itchy skin.
  • You can use Zonalon (Doxepin) for up to 8 days at a time.
  • Dalmane (flurazepam) works 15-30 minutes after taking it.
  • Dalmane (flurazepam) is available in generic.
Downsides
  • You need a prescription for Zonalon (Doxepin).
  • It isn't available as a generic, so it could be kind of pricey.
  • Zonalon (Doxepin) can make you sleepy.
  • Zonalon (Doxepin) can interact with other medications, vitamins, or alternative treatments.
  • Can make you feel sleepy and unable to concentrate the next day. This hangover effect is especially worse for women and elderly.
  • Should only be used short-term because it can be addicting.
  • Can cause sleep-walking or other sleep-related activities that you may not remember doing the next day.
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Used for
  • Skin intching (moderate)
Dosage forms
  • Cream, gel, or ointment
  • Capsule
Price
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Reviews
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Side effects
The Zonalon (Doxepin) FDA package insert doesn’t have numbers about how common side effects are.
The Dalmane (flurazepam) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Behavior changes
    • Alcohol
    • Taking narcotics, tranquilizers or antihistamines
  • Allergic reactions
  • Hangover effect
    • Women
    • Over age 65
  • Abuse and addiction
See more detailed risks and warnings