Compare doxepin vs. Dalmane

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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doxepin

Prescription only

Dalmane (flurazepam)

Prescription only
Treats depression and anxiety.

doxepin can treat depression and anxiety, but it's not a first choice medication because of its many side effects.

Helps you fall asleep.

Dalmane (flurazepam) helps you fall asleep, but its effect can carry over to the next day and be addictive.

Upsides
  • doxepin has been consistently shown to improve symptoms of depression and anxiety.
  • doxepin has been used to treat depression for over forty years.
  • Dalmane (flurazepam) works 15-30 minutes after taking it.
  • Dalmane (flurazepam) is available in generic.
Downsides
  • doxepin can make you very sleepy. Try taking it at bedtime if you need to be alert during the day.
  • You shouldn't drink alcohol with doxepin. It can worsen side effects like drowsiness.
  • You have to take it daily, especially if you are feeling better, for the medicine to do its job.
  • It can have more side effects than other antidepressants, like weight gain and increased appetite, decreased libido, and sleepiness.
  • It's not unusual for people to try different antidepressants until they find one that works for them.
  • Can make you feel sleepy and unable to concentrate the next day. This hangover effect is especially worse for women and elderly.
  • Should only be used short-term because it can be addicting.
  • Can cause sleep-walking or other sleep-related activities that you may not remember doing the next day.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Capsule
Price
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Reviews
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Side effects
The doxepin FDA package insert doesn’t have numbers about how common side effects are.
The Dalmane (flurazepam) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Suicidal thoughts or behavior
    • Age 24 years or under
  • Unmasking of bipolar disorder
    • Bipolar disorder
  • Serotonin syndrome
    • Taking MAOIs (monoamine oxidase inhibitors)
  • Heart problems
    • History of heart disease
    • Adults over 65
    • Electrolyte imbalance
  • Sleepiness
    • Adults 65 years or older
    • Taking other medicines that cause drowsiness (antihistamines, sleep medications, narcotic pain medications)
    • Alcohol
  • Dizziness and falls
    • Age 65 years or older
See more detailed risks and warnings
  • Behavior changes
    • Alcohol
    • Taking narcotics, tranquilizers or antihistamines
  • Allergic reactions
  • Hangover effect
    • Women
    • Over age 65
  • Abuse and addiction
See more detailed risks and warnings