Compare Edurant vs. Viramune

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Works with other medications to treat HIV infection.

Edurant (rilpivirine) is a good HIV drug that has to be used in combination with other HIV medications in patients who are new to treatment or are looking for alternatives to a current HIV regimen.

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  • Generally well tolerated.
  • Taken only once daily.
  • Edurant (rilpivirine) is available in other combination tablets.
  • Can be used in patients with mild or moderate kidney damage.
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  • Must be taken in combination with other HIV drugs to treat HIV. Cannot be taken alone as treatment.
  • Must be taken with a meal.
  • Cannot be taken with proton pump inhibitors (PPI) like Prilosec or Prevacid. If you need to take an acid reducer, try an antacid like calcium carbonate either 2 hours before or 4 hours after Edurant (rilpivirine). Drugs like Pepcid or Zantac (H2RAs) may also be an option, but these should be taken 12 hours before or 4 hours after Edurant (rilpivirine).
  • Not recommended for patients who have a significantly high level of viral cells or have a very low level of immune cells.
  • Not recommended for children under 12 years old.
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Used for
  • HIV infection
  • HIV infection
  • Perinatal transmission; Prophylaxis HIV infection
  • Postnatal transmission; Prophylaxis
Dosage forms
  • Pill
  • Pill
  • Liquid
  • Extended release
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Side effects
7possible side effects
  • Depressive disorders
  • Headache
  • Insomnia
  • Rash
  • Abdominal pain
  • Fatigue
  • Abnormal dreams
See more detailed side effects
The Viramune (Nevirapine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Mood and behavior changes
    • History of mental health problems
  • Immune reconstitution syndrome
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Fat Redistribution
  • Allergic reactions
    • Prior severe allergic reaction to Edurant (rilpivirine)
  • Liver damage
    • History of liver damage
    • Hepatitis B or C
  • Heart rhythm problems
    • Use with other QT prolonging drugs
    • History of heart disease
    • High doses of Edurant
See more detailed risks and warnings
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