Compare Eldepryl vs. carbidopa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Eldepryl (selegiline)

Prescription only

Lodosyn (carbidopa)

Prescription only
Treats Parkinson's disease.

Used with other medicines for Parkinson's disease to boost its effect.

Treats Parkinson's disease when given with levodopa.

Lodosyn (carbidopa) enhances the effect of levodopa. It cannot relieve symptoms of Parkinson's disease when taken by itself.

  • There are two different versions of Eldepryl (selegiline), a quick dissolving tablet and a regular tablet.
  • Eldepryl (selegiline) is one of the recommended medicines you can take along with carbidopa/levodopa if your Parkinson's disease is getting worse.
  • Extra doses of Lodosyn (carbidopa) allows you to get more out of levodopa, especially in later stages of the disease.
  • It is available in a combination pill with levodopa once you find the right dose that works for you.
  • You may have to limit the amount of cheese, smoked meat, and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
  • Can keep you up at night if you take it later in the day
  • Doesn't work by itself to treat Parkinson's disease.
  • Your doctor may need to change the dose of Lodosyn (carbidopa) frequently before finding the right dose.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Pill
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Side effects
11possible side effects
  • Skin irritation at the patch
  • Headache
  • Insomnia
  • Diarrhea
  • Dry mouth
  • Weight loss of at least 5%
  • Indigestion
  • Rash
  • Sore throat
  • Sinus infection
  • Weight gain of at least 5%
See more detailed side effects
The Lodosyn (carbidopa) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased blood pressure
    • Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
    • Taking cough and cold medicines like dextromethorphan (Robitussin DM), pseudoephedrine (Sudafed)
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
  • Increased risk of skin cancer
  • Falling asleep during the day
    • Taking other medicines for Parkinson's
  • Low blood pressure
See more detailed risks and warnings