Compare Eldepryl vs. Duopa
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Used with other medicines for Parkinson's disease to boost its effect.
Treats advanced stages of Parkinson's disease.
Duopa (carbidopa / levodopa) pumps carbidopa/levodopa into your body throughout the day. It is reserved for advanced Parkinson's disease when your symptoms become more frequent than the dosing of your tablets.
Upsides
- There are two different versions of Eldepryl (selegiline), a quick dissolving tablet and a regular tablet.
- Eldepryl (selegiline) is one of the recommended medicines you can take along with carbidopa/levodopa if your Parkinson's disease is getting worse.
- Duopa (carbidopa / levodopa) allows you to have better control of your symptoms than oral tablets, especially in later stages of Parkinson's disease.
Downsides
- You may have to limit the amount of cheese, smoked meat, and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
- Can keep you up at night if you take it later in the day
- Doesn't work by itself to treat Parkinson's disease.
- Given via pump so you'll need to have a procedure to attach the pump to your body.
- You'll need to take good care of the pump so that it doesn't get disconnected or infected.
- Duopa (carbidopa / levodopa) only lasts for 16 hours. You may need to take an extra dose of carbidopa/levodopa as tablet for nighttime control.
- You need to keep Duopa (carbidopa / levodopa) in a fridge, but it should sit at room temperature 20 minutes before infusion.
Used for
Dosage forms
- Pill
- Dissolving tablet
- Liquid
Price
Lowest price
$2100.70
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$9.20
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Side effects
11possible side effects
- Skin irritation at the patch24%
- Headache18%
- Insomnia12%
- Diarrhea9%
- Dry mouth8%
- Weight loss of at least 5%5%
- Indigestion4%
- Rash4%
- Sore throat3%
- Sinus infection3%
- Weight gain of at least 5%2%
26possible side effects
- Problems with J-tube56%
- Nausea30%
- Constipation22%
- Redness and swelling at the J-tube site19%
- Difficulty controlling movements14%
- Depression11%
- Discharge at the J-tube site11%
- Swelling in the arms and legs8%
- High blood pressure8%
- Flu and cold8%
- Sore throat8%
- Collapsed lung8%
- Confusion8%
- Anxiety8%
- Dizziness8%
- Hiatal hernia8%
- Intestinal blockage5%
- Sleep problems5%
- Fever5%
- Scar tissue5%
- Rash5%
- Urinary tract infection5%
- Hallucinations5%
- Psychotic disorder5%
- Diarrhea5%
- Indigestion5%
Risks and risk factors
- Increased blood pressure
- Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
- Taking cough and cold medicines like dextromethorphan (Robitussin DM), pseudoephedrine (Sudafed)
- Serotonin syndrome
- Tricyclic antidepressants
- Fentanyl
- Tramadol
- Buspirone
- ADHD medicines
- Triptans
- Increased risk of skin cancer
- Falling asleep during the day
- Taking other medicines for Parkinson's
- Low blood pressure
- Stomach problems
- Surgery to place the J-tube
- Falling asleep during the day
- Taking other medicines for Parkinson's
- High fever and confusion
- Stopping Duopa (carbidopa / levodopa) suddenly
- Changes in behavior
- Lack of impulse control
- Taking other medicines for Parkinson's disease