Compare Eliquis vs. Pradaxa

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Eliquis (apixaban)

Prescription only

Pradaxa (dabigatran)

Prescription only
Prevents blood clots.

Eliquis (apixaban) is an effective way to prevent blood clots from forming in your veins, but you have to take it twice a day, and your doctor might have to change the dose a lot.

3.8/ 5 average rating with 19 reviewsforEliquis
Prevents and treats blood clots.

Pradaxa (dabigatran) is an effective oral medicine for preventing and treating blood clots, but it can increase the risk of bleeding especially in older people and those with kidney problems.

Upsides
  • Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
  • You don't need to have regular blood tests on Eliquis (apixaban), and you don't have to regulate your diet like other blood thinners.
  • If you've had clots in your legs or lungs before, Eliquis (apixaban) can lower the risk of these forming again.
  • Pradaxa (dabigatran) doesn't require regular blood tests or frequent dose changes, unlike Coumadin.
  • Works just as well as other blood thinners in lowering the risk of stroke and heart attacks.
  • In cases of accidental overdose, an antidote is available to reverse the effects of the medicine.
  • May be taken with or without food.
Downsides
  • You can bruise easier and if you cut yourself, it'll take longer to stop the bleeding. Always look for signs of internal bleeding, such as dark urine or bloody stools.
  • Can't be used if you have artificial heart valves.
  • Never stop taking Eliquis (apixaban) without talking to your doctor first.
  • Eliquis (apixaban) isn't available as a generic, so it can be expensive.
  • If you've taken too much Eliquis (apixaban) and you're bleeding, it can be harder to treat compared to other blood thinners.
  • Pradaxa (dabigatran) is not available in generic form so it can be expensive.
  • Might not be a good option for people age 75 or older and those with kidney problems due to the increased risk of bleeding.
  • Not safe to be used in people with artificial heart valves.
  • Pradaxa (dabigatran) is associated with a higher risk of stomach bleeding compared to Coumadin.
  • Might not be appropriate for people who need to take aspirin or NSAIDs (such as ibuprofen) regularly since it can add to the risk of bleeding.
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Reviews
19 reviews so far
47%
saidit'sworth it
58%
saiditworked well
21%
saidit'sa big hassle

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Side effects
1possible side effects
  • Major bleed
    2%
See more detailed side effects
2possible side effects
  • Any bleeding
    11%
  • Non-major bleeding
    5%
See more detailed side effects
Risks and risk factors
  • Increased risk of stroke or blood clots from early discontinuation
    • Stopping Eliquis (apixaban) prematurely
  • Paralysis in the spine
    • Spinal puncture (spinal tap)
    • Getting anesthesia in the spine (epidural anesthesia)
    • History of spinal surgery
    • Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs), or other blood-thinners
  • Interactions with other drugs
  • Increased risk of stroke or bleeding
    • Artificial heart valve
  • Increased side effects in kidney or liver conditions
    • Current kidney problems
    • Current liver problems
See more detailed risks and warnings
  • Blood clots
    • Stopping Pradaxa (dabigatran) suddenly
  • Blood clots in the spine
    • People who have done a spinal tap or had a local anesthetic medicine injected into their spine
  • Increased risk of bleeding
    • Taking other medicines that also increase bleeding risk such as NSAIDs, aspirin, or blood thinners
    • People with kidney problems
    • People age 75 or older
  • People with artificial heart valves
    • People with artificial heart valve(s)
See more detailed risks and warnings