Compare Enablex vs. Vesicare

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Enablex (darifenacin)

Prescription only

Vesicare (solifenacin)

Prescription only
Treats overactive bladder.

Enablex (darifenacin) is a good treatment for overactive bladder if exercises and other methods haven't worked.

Treats overactive bladder.

Vesicare (solifenacin) is a good choice for treatment of overactive bladder if exercises and other behavioral methods haven't worked.

Upsides
  • Enablex (darifenacin) is effective at treating overactive bladder by lowering the urge to urinate, and helping to better control urination.
  • The tablet is available as a generic.
  • Enablex (darifenacin) is only taken once a day.
  • Vesicare (solifenacin) helps you to urinate less often.
  • Its once daily dosing is more convenient than other medicines that work like it.
Downsides
  • Enablex (darifenacin) is only recommended after doing exercises, bladder training and changes to your lifestyle haven't helped.
  • Enablex (darifenacin) can cause drowsiness and dizziness and can increase your risk for falls.
  • Enablex (darifenacin) can cause severe dry mouth and eyes and constipation.
  • Generally not recommended if you are 65 or older.
  • Do not use if you have uncontrolled narrow-angle glaucoma.
  • Can cause drowsiness and increase the risk of falls, especially in the elderly.
  • Not a good option if you have untreated, narrow-angle glaucoma.
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Reviews
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Side effects
9possible side effects
  • Dry mouth
    35%
  • Constipation
    21%
  • Indigestion
    8%
  • Urinary tract infection
    5%
  • Stomach pain
    4%
  • Weakness
    3%
  • Nausea
    2%
  • Dizziness
    2%
  • Dry eyes
    2%
See more detailed side effects
8possible side effects
  • Dry mouth
    11%
  • Constipation
    5%
  • Blurry vision
    4%
  • Urinary tract infection
    3%
  • Nausea
    2%
  • Upper abdominal pain
    2%
  • Flu
    2%
  • Dizziness
    2%
See more detailed side effects
Risks and risk factors
  • Face, lips, neck or throat swelling
  • Dizziness and drowsiness
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Trouble urinating & stomach problems
    • History of bladder problems
    • History of stomach or intestine problems
  • Liver problems
    • History of liver problems
See more detailed risks and warnings
  • Tissue swelling
  • Drowsiness
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Urinary blockage
    • Bladder outflow obstruction
  • Worsening side effects
    • History of kidney problems
    • People age 65 or older
  • Temperature dysregulation
    • Outside in hot weather
    • Dehydrated
    • Exercising
    • Added people 65 and older per Beer's Criteria
    • People age 65 and older
See more detailed risks and warnings