Compare Enalapril vs. felodipine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Vasotec (Enalapril)

Prescription only

Plendil (felodipine)

Prescription only
Lowers blood pressure.

Enalapril is a good blood pressure-lowering medicine that protects kidney function.

3.2/ 5 average rating with 95 reviewsforEnalapril
Lowers blood pressure.

Plendil (felodipine) works well to lower blood pressure, but it may cause swelling in your arms and legs at higher doses.

Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • The only ACE inhibitor that doctors can give through an IV if that's needed.
  • Plendil (felodipine) is a good option for people with high blood pressure.
  • Calcium channel blockers sometimes work better for people of African descent than other blood pressure lowering drugs.
Downsides
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Compared to other ACE inhibitors, less flexible on when you take it. Enalapril needs to be taken multiple times a day on an empty stomach.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Plendil (felodipine) may not work as well as other calcium channel blockers.
  • It can lead to more swelling in your arms and legs when taken at higher doses.
  • You can't miss doses. Stopping Plendil (felodipine) could cause a sudden spike in blood pressure.
  • Plendil (felodipine) can't be crushed or cut into two.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Extended release
Price
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Reviews
95 reviews so far
44%
saidit'sworth it
40%
saiditworked well
21%
saidit'sa big hassle

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Side effects
14possible side effects
  • Dizziness
    8%
  • Hypotension
    7%
  • Orthostatic Effects
    2%
  • Syncope
    2%
  • Chest Pain
    2%
  • Fatigue
    2%
  • Abdominal Pain
    2%
  • Asthenia
    2%
  • Orthostatic Hypotension
    2%
  • Angina Pectoris
    2%
  • Diarrhea
    2%
  • Headache
    2%
  • Vertigo
    2%
  • Cough
    2%
See more detailed side effects
8possible side effects
  • Headache
    10%
  • Swelling
    9%
  • Flushing
    5%
  • Racing heart beat
    4%
  • Weakness
    3%
  • Dizziness
    3%
  • Nausea
    2%
  • Colds or flu
    2%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Cough
  • Unusual tongue swelling
    • African descent
  • Heart problems due to high potassium
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
See more detailed risks and warnings
  • Low blood pressure
    • Over age 65
  • Heart failure
    • Taking in combination with a beta-blocker
  • Special dosing requirements
    • Liver disease
    • Over age 65
  • Swelling in arms and legs
    • History of heart failure
    • History of kidney disease
See more detailed risks and warnings