Compare Enalapril vs. Losartan

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Vasotec (Enalapril)

Prescription only

Cozaar (Losartan)

Prescription only
Lowers blood pressure.

Enalapril is a good blood pressure-lowering medicine that protects kidney function.

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3.2/ 5 average rating with 95 reviewsforEnalapril
Lowers blood pressure.

Cozaar (Losartan) is a good blood pressure-lowering medicine that protects kidney function like an ACE inhibitor, but with fewer side effects.

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3.7/ 5 average rating with 535 reviewsforLosartan
Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • The only ACE inhibitor that doctors can give through an IV if that's needed.
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Similar to ACE inhibitors (like Lisinopril), with fewer side effects like cough and swelling.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides
  • Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Compared to other ACE inhibitors, less flexible on when you take it. Enalapril needs to be taken multiple times a day on an empty stomach.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Not safe to use if you're pregnant.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
Price
Lowest price
$540.94
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Lowest price
$313.57
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Reviews
95 reviews so far
44%
saidit'sworth it
40%
saiditworked well
21%
saidit'sa big hassle

Have you used Vasotec (Enalapril)?

Leave a review
535 reviews so far
57%
saidit'sworth it
48%
saiditworked well
16%
saidit'sa big hassle

Have you used Cozaar (Losartan)?

Leave a review
Side effects
14possible side effects
  • Dizziness
    8%
  • Hypotension
    7%
  • Orthostatic Effects
    2%
  • Syncope
    2%
  • Chest Pain
    2%
  • Fatigue
    2%
  • Abdominal Pain
    2%
  • Asthenia
    2%
  • Orthostatic Hypotension
    2%
  • Angina Pectoris
    2%
  • Diarrhea
    2%
  • Headache
    2%
  • Vertigo
    2%
  • Cough
    2%
See more detailed side effects
4possible side effects
  • Upper respiratory infection
    8%
  • Dizziness
    3%
  • Back pain
    2%
  • Nasal congestion
    2%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Cough
  • Unusual tongue swelling
    • African descent
  • Heart problems due to high potassium
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
See more detailed risks and warnings
  • Harm to fetus
    • Women of childbearing age
  • Liver damage
    • Concurrent liver disease
  • Heart problems due to high potassium
    • Current kidney problems
    • Medicine that increase potassium
    • Use of salt substitute
See more detailed risks and warnings
Learn more about Vasotec (Enalapril)
Learn more about Cozaar (Losartan)