Compare entacapone vs. Azilect
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Comtan (entacapone) enhances the effect of carbidopa/levodopa. It's usually added on when carbidopa/levodopa starts to lose its effect on Parkinson's disease.
Treats Parkinson's disease.
Azilect (rasagiline) is one of the recommended medicines to treat Parkinson's disease. It is now available in generic, which makes it more affordable for people without insurance.
Upsides
- Allows you to get more out of carbidopa/levodopa, especially in later stages of Parkinson's disease.
- Comtan (entacapone) is available in a single pill combination with carbidopa/levodopa.
- Azilect (rasagiline) is one of the go-to medicines for Parkinson's disease. It can be used in early and late stages of the disease.
- Taking Azilect (rasagiline) by itself can help slow down Parkinson's disease, but it works better when it's given with other medicines.
- Azilect (rasagiline) is available as generic as well as brand name, so there are usually lower out-of-pocket costs for you with insurance.
Downsides
- Must be taken with other medicines for Parkinson's disease
- Can make you lightheaded especially if you suddenly stand up from sitting or lying down.
- Can make you very sleepy
- May require frequent adjustments before finding the dose that works best for you
- It can cause unusual cravings and changes in behavior in some people.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$2572.13
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$52.30
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Reviews
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Side effects
21possible side effects
- Difficulty controlling movements25%
- Nausea14%
- Muscle spasm10%
- Changes in urine color10%
- Diarrhea10%
- Muscle rigidity9%
- Dizziness8%
- Abdominal pain8%
- Fatigue6%
- Constipation6%
- Vomiting4%
- Dry mouth3%
- Shortness of breath3%
- Purple spots on the skin3%
- Increased sweating2%
- Back pain2%
- Anxiety2%
- Sleepiness2%
- Indigestion2%
- Flatulence2%
- Weakness2%
46possible side effects
- Difficulty controlling movement18%
- Headache14%
- Accidental injury12%
- Nausea12%
- Falls11%
- Weight loss9%
- Constipation9%
- Low blood pressure9%
- Joint pain8%
- Indigestion7%
- Dizziness7%
- Swelling in arms and legs7%
- Vomiting7%
- Dry mouth6%
- Rash6%
- Sleepiness6%
- Depression5%
- Flu-like symptoms5%
- Abdominal pain5%
- Loss of appetite5%
- Diarrhea5%
- Bruising5%
- Tingling or prickling sensation5%
- Back pain4%
- Cough4%
- Trouble sleeping4%
- Cold or flu4%
- Unusual dreams4%
- Hallucinations4%
- Eyelid problems3%
- Fever3%
- Stomach infection3%
- Stuffy nose3%
- Movement coordination problems3%
- Shortness of breath3%
- Infections3%
- Neck pain3%
- Sweating3%
- Tendon swelling3%
- Uncontrollable muscle movements3%
- Arthritis2%
- Weakness2%
- Gum swelling2%
- Excessive bleeding2%
- Hernia2%
- Muscle weakness2%
Risks and risk factors
- Falling asleep during the day
- Taking other medicines for Parkinson's
- Changes in behavior
- Low blood pressure and fainting
- Low blood pressure
- Taking medicines for high blood pressure
- Lack of impulse control
- Taking other medicines for Parkinson's disease
- Diarrhea
- Difficulty controlling movements
- Increased blood pressure
- Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
- Serotonin syndrome
- Tricyclic antidepressants
- Fentanyl
- Tramadol
- Buspirone
- ADHD medicines
- Triptans
- dextromethorphan
- pseudoephedrine
- Falling asleep during the day
- Taking other medicines for Parkinson's disease
- Low blood pressure
- Movement problems
- Taking other medicines for Parkinson's disease
- Lack of impulse control
- Taking other medicines for Parkinson's disease