Compare entacapone vs. carbidopa
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Comtan (entacapone) enhances the effect of carbidopa/levodopa. It's usually added on when carbidopa/levodopa starts to lose its effect on Parkinson's disease.
Treats Parkinson's disease when given with levodopa.
Lodosyn (carbidopa) enhances the effect of levodopa. It cannot relieve symptoms of Parkinson's disease when taken by itself.
Upsides
- Allows you to get more out of carbidopa/levodopa, especially in later stages of Parkinson's disease.
- Comtan (entacapone) is available in a single pill combination with carbidopa/levodopa.
- Extra doses of Lodosyn (carbidopa) allows you to get more out of levodopa, especially in later stages of the disease.
- It is available in a combination pill with levodopa once you find the right dose that works for you.
Downsides
- Must be taken with other medicines for Parkinson's disease
- Can make you lightheaded especially if you suddenly stand up from sitting or lying down.
- Can make you very sleepy
- May require frequent adjustments before finding the dose that works best for you
- Your doctor may need to change the dose of Lodosyn (carbidopa) frequently before finding the right dose.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$101.83
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$2651.63
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Reviews
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Side effects
21possible side effects
- Difficulty controlling movements25%
- Nausea14%
- Muscle spasm10%
- Changes in urine color10%
- Diarrhea10%
- Muscle rigidity9%
- Dizziness8%
- Abdominal pain8%
- Fatigue6%
- Constipation6%
- Vomiting4%
- Dry mouth3%
- Shortness of breath3%
- Purple spots on the skin3%
- Increased sweating2%
- Back pain2%
- Anxiety2%
- Sleepiness2%
- Indigestion2%
- Flatulence2%
- Weakness2%
The Lodosyn (carbidopa) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Falling asleep during the day
- Taking other medicines for Parkinson's
- Changes in behavior
- Low blood pressure and fainting
- Low blood pressure
- Taking medicines for high blood pressure
- Lack of impulse control
- Taking other medicines for Parkinson's disease
- Diarrhea
- Difficulty controlling movements
- Take with levodopa