Compare entacapone vs. Requip
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats Parkinson's disease.
Comtan (entacapone) enhances the effect of carbidopa/levodopa. It's usually added on when carbidopa/levodopa starts to lose its effect on Parkinson's disease.
Helps with movement problems.
Requip (Ropinirole) is an effective medicine for Parkinson's disease or restless leg syndrome, but there are potentially serious side effects.
Upsides
- Allows you to get more out of carbidopa/levodopa, especially in later stages of Parkinson's disease.
- Comtan (entacapone) is available in a single pill combination with carbidopa/levodopa.
- In studies, Requip (Ropinirole) when taken by itself or with other medicines, was effective in lowering movement fluctuations for people with Parkinson's disease.
- Requip (Ropinirole) is sometimes preferred over other medicines that treat Parkinson's disease in older people since it causes fewer movement and mental fluctuations.
- Is effective for treating restless leg syndrome.
- Available in a short-acting and a long-acting form.
Downsides
- Must be taken with other medicines for Parkinson's disease
- Can make you lightheaded especially if you suddenly stand up from sitting or lying down.
- Can make you very sleepy
- May require frequent adjustments before finding the dose that works best for you
- Requip (Ropinirole) isn't a first-choice treatment for Parkinson's disease. It can be used by itself, but it's usually used with other medicines.
- Requip (Ropinirole) can cause hallucinations in older people.
- Not the best choice if you have kidney problems. Your doctor may have to adjust your dose based on your kidney function.
- You can't suddenly stop taking Requip (Ropinirole). You'll have to slowly lower your dose, especially if you've been using it for a long time.
Used for
Dosage forms
- Pill
- Pill
- Extended release
Price
Lowest price
$240.41
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$18.72
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Reviews
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Side effects
21possible side effects
- Difficulty controlling movements25%
- Nausea14%
- Muscle spasm10%
- Changes in urine color10%
- Diarrhea10%
- Muscle rigidity9%
- Dizziness8%
- Abdominal pain8%
- Fatigue6%
- Constipation6%
- Vomiting4%
- Dry mouth3%
- Shortness of breath3%
- Purple spots on the skin3%
- Increased sweating2%
- Back pain2%
- Anxiety2%
- Sleepiness2%
- Indigestion2%
- Flatulence2%
- Weakness2%
49possible side effects
- Dyskinesia34%
- Nausea30%
- Dizziness26%
- Adverse events24%
- Somnolence20%
- Headache17%
- Falls10%
- Hallucinations10%
- Abdominal pain9%
- Confusion9%
- Upper respiratory tract infection9%
- Hallucination8%
- Increased sweating7%
- Increased drug level7%
- Vomiting7%
- Arthralgia7%
- Abdominal pain/discomfort6%
- Adverse reactions6%
- Tremor6%
- Constipation6%
- Anxiety6%
- Urinary tract infection6%
- Orthostatic hypotension5%
- Dry mouth5%
- Pain5%
- Hypokinesia5%
- Paresthesia5%
- Diarrhea5%
- Amnesia5%
- Nervousness5%
- Vertigo4%
- Edema peripheral4%
- Back pain3%
- Hypertension3%
- Syncope3%
- Paresis3%
- Arthritis3%
- Abnormal dreaming3%
- Dyspnea3%
- Fall/injury2%
- Hypotension2%
- Dysphagia2%
- Flatulence2%
- Increased saliva2%
- Weight decrease2%
- Anemia2%
- Pyuria2%
- Urinary incontinence2%
- Diplopia2%
Risks and risk factors
- Falling asleep during the day
- Taking other medicines for Parkinson's
- Changes in behavior
- Low blood pressure and fainting
- Low blood pressure
- Taking medicines for high blood pressure
- Lack of impulse control
- Taking other medicines for Parkinson's disease
- Diarrhea
- Difficulty controlling movements
- Impulse control problems
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Low blood pressure
- Taking blood pressure-lowering medicines
- Worsening kidney function
- Current kidney problems
- Skin cancer
- Parkinson's disease
- Hallucinations
- Age 65 years or older