Compare Epclusa vs. Copegus

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Epclusa (velpatasvir / sofosbuvir)

Prescription only

Copegus (Ribavirin)

Treats hepatitis C.

Epclusa (velpatasvir / sofosbuvir) is a combination medicine that treats hepatitis C, and has been shown very effective at curing the disease in many people. It is very expensive.

No information currently available

Upsides

Epclusa (velpatasvir / sofosbuvir) is the first medicine approved to treat all genotypes of hepatitis C.
Most people only have to take one pill of Epclusa (velpatasvir / sofosbuvir) once a day for 12 weeks. If you have severe liver damage, you'll have to take it with ribavirin.
It can be taken with or without food.
The most common side effects are usually mild, including fatigue and headache.

No information currently available

Downsides

Epclusa (velpatasvir / sofosbuvir) can only be absorbed properly in an acidic stomach so heartburn meds can affect how well it works.
Epclusa (velpatasvir / sofosbuvir) can cause serious drops in heart rate when it is taken with amiodarone.
If you have severe liver disease, you'll have to take Epclusa (velpatasvir / sofosbuvir) with another medication called ribavirin.

No information currently available

Used for

Hepatitis C

Hematopoietic stem cell transplant - Respiratory syncytial virus infection Hepatitis C
Chronic
Combination therapy in interferon alfa-naive patients with compensated liver disease - HIV infection Hepatitis C
Chronic
With compensated liver disease Respiratory syncytial virus infection
Herpes simplex Influenza Viral hemorrhagic fever

Dosage forms