Compare Epzicom vs. Combivir

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT
Works with other medicines to treat HIV infection.

Epzicom (abacavir / lamivudine) contains two medicines in one tablet, used with other medicines, to treat HIV infection. Your doctor does need to test you before you start it to make sure you don't get an allergic reaction.

Treats HIV infection

While Combivir (lamivudine / zidovudine) isn't one of the first choices for treating HIV, it can still be an option if other HIV medications aren't working well for you.

Upsides
  • Epzicom (abacavir / lamivudine) contains two first choice medicines used in combination with other medicines to treat HIV infections.
  • Compared to other HIV medicines, Epzicom (abacavir / lamivudine) does not have as many drug interactions with other medicines.
  • Can be taken with or without food.
  • Epzicom (abacavir / lamivudine) can be taken by children weighng at least 55lbs (25kg) or more.
  • Combivir (lamivudine / zidovudine) can be taken with or without food.
  • Combivir (lamivudine / zidovudine) can be taken by children and adolescents weighing 30kg (66lbs) or more.
  • Available in generic.
Downsides
  • Epzicom (abacavir / lamivudine) isn't recommended if you'll need to adjust the dose of medications due to problems like kidney and/or liver damage.
  • Epzicom (abacavir / lamivudine) can increase your risk of heart attack, especially if you have other heart-related issues such as high blood pressure, high cholesterol, diabetes, or if you smoke.
  • Severe allergic reactions have happened in some patients taking Epzicom (abacavir / lamivudine). Your doctor will test you for any possible risk of reaction before starting Epzicom (abacavir / lamivudine).
  • Combivir (lamivudine / zidovudine) needs to be taken twice daily.
  • Combivir (lamivudine / zidovudine) may cause serious blood, muscle, and liver problems.
  • Combivir (lamivudine / zidovudine) is not recommended if you have kidney damage.
  • Combivir (lamivudine / zidovudine) can cause a lot of side effects, including nausea, vomiting, loss of appetite, headache, and malaise.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Pill
Price
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
13possible side effects
  • Severe allergic reaction
    9%
  • Insomnia
    7%
  • Depression/Depressed mood
    7%
  • Headache/Migraine
    7%
  • Fatigue/Malaise
    6%
  • Dizziness/Vertigo
    6%
  • Nausea
    5%
  • Diarrhea
    5%
  • Rash
    5%
  • Fever
    5%
  • Abdominal pain & inflammation
    4%
  • Abnormal dreams
    4%
  • Anxiety
    3%
See more detailed side effects
20possible side effects
  • Headache
    35%
  • Nausea
    33%
  • Malaise and fatigue
    27%
  • Nose-related problems
    20%
  • Diarrhea
    18%
  • Cough
    18%
  • Nausea and vomiting
    13%
  • Nerve problems
    12%
  • Bone pain
    12%
  • Insomnia and other sleep disorders
    11%
  • Fever or chills
    10%
  • Loss or decrease in appetite
    10%
  • Dizziness
    10%
  • Abdominal pain
    9%
  • Depression
    9%
  • Skin rashes
    9%
  • Muscle pain
    8%
  • Abdominal cramps
    6%
  • Indigestion
    5%
  • Joint pain
    5%
See more detailed side effects
Risks and risk factors
  • Severe allergic reaction
    • Previous allergic reaction to Triumeq or abacavir
    • Presence of HLA-B*5701 gene
  • Lactic acidosis and Fatty liver
    • Liver disease
    • Women
    • Obesity
  • Acute exacerbation of hepatitis B virus (HBV)
    • Hepatitis B virus
  • Fat redistribution
    • HIV treatment
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Heart attack
    • History of coronary heart disease
    • High blood pressure
    • Dyslipidemia
    • Diabetes mellitus
    • Smoking
See more detailed risks and warnings
  • Blood and bone marrow problems
    • Advanced HIV
    • Anemia
    • Neutropenia
  • Muscle damage
    • Taking Combivir (lamivudine / zidovudine) for a long time
  • Worsening of hepatitis B
    • Hepatitis B virus
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Inflammation of the pancreas (pancreatitis)
    • History of pancreatitis
See more detailed risks and warnings