Compare Fanapt vs. Seroquel

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Fanapt (Iloperidone)

Prescription only

Seroquel (quetiapine)

Prescription only
Controls schizophrenia.

Fanapt (Iloperidone) is helpful for treating schizophrenia, but it can be expensive because it's only available as brand name.

Helps control your thoughts and mood.

Seroquel (quetiapine) is a effective at treating schizophrenia, mania, and depression but it can cause weight gain and high blood glucose levels.

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3.7/ 5 average rating with 250 reviewsforSeroquel
Upsides
  • Part of the first choice medications to treat schizophrenia.
  • There are patient assistance programs that can lower the copay.
  • Comes in many different strengths to make it easier to customize your dose.
  • Less likely to cause sexual problems than other similar medicines.
  • Seroquel (quetiapine) is effective at relieving psychotic symptoms and manic episodes.
  • Seroquel (quetiapine) has fewer side effects than most antipsychotic medications.
  • Seroquel (quetiapine) is less likely to cause heart problems compared to some other antipsychotics.
  • Seroquel (quetiapine) is also the least likely to cause Extrapyramidal Symptoms (EPS) – a movement disorder that causes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
Downsides
  • Fanapt (Iloperidone) can be expensive because it is only available as brand name.
  • You will need to follow a strict schedule the first two weeks as body adjusts to Fanapt (Iloperidone). You might have to see your doctor several times until you find a dose that works best for you.
  • You're more likely to have changes in blood pressure with Fanapt (Iloperidone), which can make you feel faint or dizzy.
  • If you stop taking Fanapt (Iloperidone) for 3 days and want to restart it, you'll have to start taking it from the beginning dose.
  • You have to take Fanapt (Iloperidone) twice a day, which can be hard to remember.
  • Seroquel (quetiapine) has a moderate to high risk of weight gain, elevated cholesterol and/or blood sugar compared to other antipsychotics.
  • You might need routine blood tests to check how Seroquel (quetiapine) is affecting your body.
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Used for
Dosage forms
  • Pill
  • Pill
  • Extended release
Price
Lowest price
$1982.48
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Lowest price
$13.06
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Reviews
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250 reviews so far
56%
saidit'sworth it
50%
saiditworked well
27%
saidit'sa big hassle

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Side effects
20possible side effects
  • Dizziness
    10%
  • Sleepiness
    9%
  • Dry mouth
    8%
  • Nausea
    7%
  • Diarrhea
    5%
  • Difficulty controlling movements
    5%
  • Agitation
    5%
  • Nasal congestion
    5%
  • Fatigue
    4%
  • Sore throat
    4%
  • Joint pain
    3%
  • Faster heart rate
    3%
  • Blurred vision
    3%
  • Tremor
    3%
  • Sluggishness
    3%
  • Rash
    3%
  • Sudden changes in blood pressure
    3%
  • Colds or flu
    2%
  • Ejaculation disorder
    2%
  • Difficulty breathing
    2%
See more detailed side effects
36possible side effects
  • Drowsiness
    34%
  • Dry mouth
    19%
  • Headache
    17%
  • Weakness
    10%
  • Constipation
    10%
  • Dizziness
    9%
  • Tremor
    8%
  • Stomach pain
    7%
  • Low blood pressure
    7%
  • Agitation
    6%
  • Weight gain
    6%
  • Sore throat
    6%
  • Back pain
    5%
  • Stiffness/difficulty moving
    4%
  • Hay fever
    4%
  • Swelling in the limbs
    4%
  • Twitching
    4%
  • Indigestion
    4%
  • Depression
    3%
  • Lazy eye
    3%
  • Speech disorder
    3%
  • Altered hormone levels
    3%
  • Heaviness
    2%
  • Infection
    2%
  • Fever
    2%
  • High blood pressure
    2%
  • Increased heart rate
    2%
  • Increased appetite
    2%
  • Hypothyroidism
    2%
  • Incoordination
    2%
  • Abnormal thinking
    2%
  • Anxiety
    2%
  • Loss of control of movements
    2%
  • Sinus infection
    2%
  • Sweating
    2%
  • Urinary Tract Infection
    2%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • People over 65 with dementia and psychosis
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Higher blood sugar, cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
  • Difficulty controlling movements
    • Long-term use of atypical antipsychotics
  • Blood disorders
  • Changes in blood pressure and heart beat
    • High blood pressure
    • History of heartbeat problems
See more detailed risks and warnings
  • Higher risk of death
    • Elderly patients with dementia-related psychosis
  • Suicidal thoughts or behavior
    • Children, adolescents, and young adults (<24 years old)
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Extrapyramidal Symptoms (EPS)
  • Metabolic changes (increased blood sugar, high cholesterol and weight gain)
    • People with diabetes
    • People with high cholesterol
See more detailed risks and warnings
Learn more about Fanapt (Iloperidone)
Learn more about Seroquel (quetiapine)