Compare Farxiga vs. glyburide

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Farxiga (dapagliflozin)

Prescription only

Diabeta (glyburide)

Prescription only
Lowers blood sugar.

Farxiga (dapagliflozin) can be used together with other diabetes medicines to help lower your blood sugar, but it can be expensive because it's brand name.

Lowers blood sugar.

Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.

3.3/ 5 average rating with 110 reviewsforglyburide
  • Can lower A1c by 1% (A1c measures your average blood sugar over time.)
  • Can help you lose weight.
  • Less chance of low blood sugar than other diabetes medicines.
  • Available as an oral tablet.
  • Lowers your A1c (average blood sugar over time) up to 2%.
  • Available in generic version.
  • Available in single pill combination with other anti-diabetic medicines.
  • Not a first choice medicine for diabetes because it doesn't lower blood sugar as much as other medicines.
  • Higher risk of genital yeast infections and urinary tract infections.
  • This is an expensive medication with no generic available at this time.
  • Not shown to improve cardiovascular outcomes like other similar medicines because it can increase cholesterol.
  • Not a good choice if you drink a lot of alcohol.
  • More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
  • You will have to check your blood sugar often when you first start taking it.
  • Can cause weight gain (about 2 to 3 pounds).
  • Not ideal for elderly or those with poor kidney function.
  • May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Used for
Dosage forms
  • Pill
  • Pill
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Side effects
13possible side effects
  • Female yeast infection
  • Common cold symptoms
  • Urinary tract infection
  • Back pain
  • Increased urination
  • Male yeast infection
  • Nausea
  • Flu
  • Increased cholesterol
  • Constipation
  • Discomfort with urination
  • Pain in hands and feet
  • Mild low blood sugar
See more detailed side effects
2possible side effects
  • Nausea and heartburn
  • Skin allergies
See more detailed side effects
Risks and risk factors
  • Genital yeast infection
  • Urinary tract infection
  • Low blood pressure
    • Taking water pills for blood pressure
    • Over age 65
    • Kidney problems
  • Kidney problems
    • Kidney damage
    • Taking water pills, ACE inhibitors or ARBs for blood pressure
    • Anti-inflammatory medicines (NSAIDs)
    • Heart failure
  • Increased acid and ketones in the blood
    • Long periods of fasting
    • Alcohol abuse
    • Dehydration
    • History of pancreatitis
See more detailed risks and warnings
  • Low blood sugar
    • Over age 65
    • Kidney problems
    • Use of other blood sugar lowering medicines
    • Alcohol
    • Intense physical activity
  • Severe allergic reactions
    • History of sulfa allergies
See more detailed risks and warnings