Compare Flagyl vs. Minocycline

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Flagyl (metronidazole)

Prescription only

Solodyn (Minocycline)

Prescription only
Treats and prevents bacterial infections.

Flagyl (metronidazole) is very good at treating certain bacterial infections, but you can't have any alcohol while on it since it'll make you throw up a lot.

Treats bacterial infections.

Solodyn (Minocycline) is an effective way to treat certain skin infections, acne, and rosacea, but you'll need to use barrier methods of birth control since it can make birth control pills less effective and cause birth defects.

4.0/ 5 average rating with 17 reviewsforMinocycline
Upsides
  • Flagyl (metronidazole) is good at killing a variety of bacteria.
  • Unlike many other antibiotics, Flagyl (metronidazole) is less likely to make bacteria resistant to it.
  • Most forms are available as a generic, so it's relatively cheap.
  • Clinical studies show it's effective against MRSA, a common skin infection, and it's commonly used to treat acne and rosacea.
  • Available as a generic, so it should be reasonably priced.
  • Solodyn (Minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Bacteria are less likely to become resistant to Solodyn (Minocycline) than other tetracycline antibiotics.
Downsides
  • You can't drink alcohol while on Flagyl (metronidazole), and for at least 3 days after you finish it.
  • Side effects can include nausea, headache, stomach upset, and a metallic taste in your mouth.
  • If you're taking Flagyl (metronidazole) for a long time, there's a risk of more side effects, such as nerve damage.
  • If you're on blood thinners, let your doctor know. Flagyl (metronidazole) can interact with your medicines and make you more likely to bleed.
  • It can make birth control pills less effective, so people should use barrier methods of birth control like condoms or diaphragms while on Solodyn (Minocycline).
  • Can stain your teeth, mouth, and gums if you're using the tablets, or your skin if you're using the topical version, but this is temporary.
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Used for
Dosage forms
  • Pill
  • Extended-release pill
  • Injection
  • Pill
  • Extended release
  • Extended release capsule
Price
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Reviews
Not enough review data.Leave a review
17 reviews so far
53%
saidit'sworth it
59%
saiditworked well
18%
saidit'sa big hassle

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Side effects
13possible side effects
  • Headache
    18%
  • Nausea
    10%
  • Metallic taste
    9%
  • Genital itching
    5%
  • Dizziness
    4%
  • Diarrhea
    4%
  • Stomach problems
    4%
  • Overgrowth of yeast
    3%
  • Stuffy nose
    3%
  • Menstrual cramps
    3%
  • Abnormal urine
    3%
  • Dry mouth
    2%
  • Urinary tract infection
    2%
See more detailed side effects
The Solodyn (Minocycline) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Seizure or brain problems
    • Taking high doses of Flagyl (metronidazole)
    • Taking Flagyl (metronidazole) for a long time
  • Nerve damage
    • Taking high doses of Flagyl (metronidazole)
    • Taking Flagyl (metronidazole) for a long time
  • Cancer
  • New infection while taking Flagyl (metronidazole)
    • Taking Flagyl (metronidazole) incorrectly
  • Interaction with alcohol
    • Drinking alcohol while taking Flagyl (metronidazole)
See more detailed risks and warnings
  • Changes in teeth
    • Age 8 years or younger
  • Decreased effectiveness of birth control pills
    • Using oral birth control pills
  • Diarrhea from a superinfection (an infection that happens after, or in addition to, an earlier infection)
    • Long antibiotic treatment period
  • Rash
  • Sunburn
  • Harm to fetus
    • Women of childbearing age
See more detailed risks and warnings