Compare Flonase vs. Nasonex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Flonase (fluticasone)

Prescription or OTC

Nasonex (Mometasone)

Prescription only
Relieves nasal allergy symptoms.

Flonase (fluticasone) is a good first-choice treatment for allergies of the nose, but long-term use can increase the risk of nosebleeds.

3.7/ 5 average rating with 890 reviewsforFlonase
Relieves allergy symptoms.

Nasonex (Mometasone) is a good first-choice treatment for stuffy and runny noses caused by allergies.

3.6/ 5 average rating with 675 reviewsforNasonex
Upsides
  • Only need to use Flonase (fluticasone) once a day. Its effects can last for up to 24 hours.
  • Available over-the-counter and cheaper than many of its alternatives.
  • Highly effective treatment of allergy symptoms in the nose.
  • Flonase (fluticasone) gives you very little to no side effects since it's a nasal spray and doesn't expose the rest of your body to the medicine.
  • First-choice medication for treating runny and stuffy noses caused by allergies. It works by reducing inflammation in the nose.
  • Because it's used directly where the inflammation is happening, it has fewer side effects than oral steroids do and has a lower chance of causing withdrawal symptoms once the medication is stopped.
  • Can be used as needed to help control symptoms in people age 13 years or older.
  • Available as a generic, which is cheaper.
Downsides
  • Flonase (fluticasone) is not an appropriate medicine for people who have an injured nose or had a recent surgery in the nose.
  • Can slow down the growth rate in children.
  • Can increase the risk of bleeding and fungal infections in the nose.
  • Not recommended for those who are also taking other medicines that lower their ability to fight off infections.
  • Needs to be primed 10 times before it can be used, or re-primed if not used for more than 2 weeks.
  • Doesn't have a counter on it, so it can be hard to remember how many sprays are left (each bottle has 120 sprays).
  • Since the medicine in Nasonex (Mometasone) is a steroid, it can slow down your healing process if you've hurt your nose or had nose surgery.
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Used for
Dosage forms
  • Nasal spray
  • Nasal spray
Price
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Reviews
890 reviews so far
72%
saidit'sworth it
43%
saiditworked well
7%
saidit'sa big hassle

Have you used Flonase (fluticasone)?

Leave a review
675 reviews so far
68%
saidit'sworth it
39%
saiditworked well
8%
saidit'sa big hassle

Have you used Nasonex (Mometasone)?

Leave a review
Side effects
7possible side effects
  • Headache
    7%
  • Asthma-like symptoms
    7%
  • Sore throat
    6%
  • Nosebleed
    6%
  • Nausea/vomiting
    5%
  • Cough
    4%
  • Nasal burning/nasal irritation
    2%
See more detailed side effects
1possible side effects
  • Nosebleed
    13%
See more detailed side effects
Risks and risk factors
  • Decreased growth rate in children
    • Children
    • Using the medicine for a long period of time
  • Effect on wound healing
    • People who had recent surgery or injury to the nose
  • Lowered ability to fight off infections
    • People who come into contact with others who have chickenpox, measles, or tuberculosis
    • People who have not received a vaccine for chickenpox, measles, or tuberculosis
  • Damage to nose
    • Using the medicine for a long period of time
  • Sinus infection
    • People who recently had the cold or flu
  • Increased risk of nosebleeds
See more detailed risks and warnings
  • Thrush in the nose and throat
    • Long-term use
  • Changes in the nasal septum
    • Long-term use
  • Decreased wound healing
    • Surgery or trauma to the nose or sinuses
  • Glaucoma and cataracts
    • Long-term use
  • Reduced immune system
    • Exposure to immunizable diseases (chickenpox and measles)
    • Exposure to tuberculosis
  • Decrease in growth in children and teenagers
    • Long-term use
    • Taking more than recommended dose
See more detailed risks and warnings