Compare Focalin vs. Dexedrine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats attention deficit disorder.

Focalin (dexmethylphenidate) effectively treats ADHD, and is usually recommended if first-line ADHD medications don't work for you.

3.3/ 5 average rating with 141 reviewsforFocalin
Treats attention deficit disorder.

Dexedrine (dextroamphetamine) is an effective medicine for treatment of ADHD, but often abused for recreational purposes.

4.3/ 5 average rating with 28 reviewsforDexedrine
Upsides
  • Effectively treats ADHD in children and adults.
  • Extended release capsules can be opened and sprinkled in applesauce for people who don't like swallowing pills.
  • The extended release pill is available in many strengths and allows for personalized dosing.
  • Available as a generic, so it should be reasonably priced.
  • Recommended as a first-choice treatment of ADHD.
  • Available as generic version.
  • For more flexible dosing schedule, Dexedrine (dextroamphetamine) is available in short and long formulations.
  • If you have difficulty swallowing pills, Dexedrine (dextroamphetamine) is available as a liquid.
Downsides
  • Not carried by all pharmacies and may need to be special ordered for you.
  • Decreased appetite in children may affect their growth.
  • Requires a new prescription from your doctor every month so it may be a hassle for some people.
  • Has the potential for abuse, misuse, and dependence.
  • Taking Dexedrine (dextroamphetamine) can decrease your appetite.
  • If taken late in the day, Dexedrine (dextroamphetamine) can cause insomnia.
  • People who take high doses of Dexedrine (dextroamphetamine) are more likely to have anxiety, restlessness, or irritability.
  • Requires a new prescription from your doctor every month.
  • Not a good option if you have a history of seizures.
  • Can be habit-forming so make sure you use it only as prescribed.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Liquid
Price
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Reviews
141 reviews so far
55%
saidit'sworth it
35%
saiditworked well
21%
saidit'sa big hassle

Have you used Focalin (dexmethylphenidate)?

Leave a review
28 reviews so far
89%
saidit'sworth it
79%
saiditworked well
21%
saidit'sa big hassle

Have you used Dexedrine (dextroamphetamine)?

Leave a review
Side effects
The Focalin (dexmethylphenidate) FDA package insert doesn’t have numbers about how common side effects are.
The Dexedrine (dextroamphetamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Abuse and dependence
    • History of substance abuse
  • Serious or life-threatening cardiovascular events
    • History of heart problems
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of bipolar Disorder
  • Long-term growth suppression
  • Seizures
    • History of seizures
  • Blood circulation problems
See more detailed risks and warnings
  • Abuse and dependence
    • History of drug abuse
  • Serious or life-threatening heart problems
    • History of heart problems
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of bipolar disorder
  • Long-term growth suppression
    • Children
  • Seizures
    • History of seizures
  • Serotonin Syndrome (rare, life-threatening)
    • Using other medicines that increase serotonin levels in the brain
See more detailed risks and warnings