Compare Fortesta vs. Depo-Testosterone

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats low testosterone.

Fortesta (testosterone) is a convenient topical form of testosterone hormone replacement, but it can be spread to another person if skin-to-skin contact occurs.

Treats low testosterone.

This testosterone injection only has to be given once or twice a month and you can do it at home, but someone has to help you inject.

3.0/ 5 average rating with 100 reviewsforDepo-Testosterone
Upsides
  • Fortesta (testosterone) is an effective and convenient form of testosterone.
  • It is easily used. You apply it to your thighs like a lotion.
  • Putting Fortesta (testosterone) on your thighs makes it less likely that you'll transfer the medication to other people around you.
  • Fortesta (testosterone) is available as a cheaper generic form.
  • A first-choice treatment for low testosterone in men and delayed puberty in boys.
  • Available in generic.
  • Only has to be given once every 2 to 4 weeks.
  • The shot can be done at home.
Downsides
  • You have to wait at least 2 hours after applying Fortesta (testosterone) before you can swim or bathe, otherwise your body won't absorb the full amount of the medication.
  • Fortesta (testosterone) does not need to be dose adjusted if you have liver or kidney problems.
  • Only available as a shot.
  • Has to be given by someone else since it has to be injected into your buttocks.
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Used for
  • Hypogonadism
  • Low testosterone
  • Gender identity disorder (female-to-male transsexual)
Dosage forms
  • Gel
  • Injection
Price
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Reviews
Not enough review data.Leave a review
100 reviews so far
49%
saidit'sworth it
32%
saiditworked well
17%
saidit'sa big hassle

Have you used Depo-Testosterone (Testosterone Cypionate Injection)?

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Side effects
1possible side effects
  • Skin reaction
    16%
See more detailed side effects
The Depo-Testosterone (Testosterone Cypionate Injection) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Virilization from secondary exposure
  • Blood clots
  • Swelling in the legs
    • Heart disease
    • Liver disease
    • Kidney disease
  • Elevated red blood cell count
  • High calcium in the blood
    • History of cancer
  • Flammability
    • Smoking
    • Exposure to fire or flames
See more detailed risks and warnings
  • Breast tissue changes
    • Male
  • Changes in sex drive
    • Male
  • Inability to urinate
    • Enlarged prostate (benign prostatic hypertrophy)
  • Changes in sperm
    • Taking high doses of Depo-Testosterone (Testosterone Cypionate Injection)
  • Swelling in the legs
    • Heart, liver or kidney disease
  • High calcium in the blood
    • Inability to move
    • Cancer
  • Liver disease
  • Changes in mood
  • Changes in blood sugar
    • Diabetes
  • Changes in blood thinning
    • On blood thinners
  • Blood clots
See more detailed risks and warnings