Compare Fosrenol vs. Auryxia

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Fosrenol (lanthanum)

Prescription only

Auryxia (ferric citrate)

Prescription only
Lowers phosphate levels.

Fosrenol (lanthanum) works well to lower blood phosphate levels without affecting blood calcium levels in people with advanced kidney disease, but it can be expensive, and you need to take it with meals.

Lowers phosphate levels.

Auryxia (ferric citrate) is great for getting rid of excess phosphate, but not for people who have a lot of iron in their blood.

  • Works as well as other phosphate binders to lower blood phosphate levels.
  • Easy to take since Fosrenol (lanthanum) comes in powder form, and the tablet form can be crushed or chewed.
  • Is calcium-free, which means Fosrenol (lanthanum) doesn't come with the risk of high calcium levels like some alternative medicines.
  • If you have high phosphate levels, Auryxia (ferric citrate) can lower and control them.
  • If you have low levels of iron in your blood, Auryxia (ferric citrate) can help increase your levels.
  • Like other phosphate binders, Fosrenol (lanthanum) must be taken with meals.
  • Is more expensive than other phosphate binders.
  • Depending on your needs, your doctor may have you take up to 4 pills three times a day with your meals.
  • While you're on Auryxia (ferric citrate), your doctor may want to check how much iron is in your body with blood tests.
  • Auryxia (ferric citrate) is not chewable, unlike a similar phosphate-lowering drug. Auryxia (ferric citrate) must be swallowed whole.
Used for
  • Hyperphosphatemia in advanced kidney disease
  • Hyperphosphatemia
Dosage forms
  • Pill
  • Powder
  • Pill
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Side effects
3possible side effects
  • Nausea
  • Vomiting
  • Stomach pain
See more detailed side effects
5possible side effects
  • Diarrhea
  • Nausea
  • Constipation
  • Vomiting
  • Cough
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Risks and risk factors
  • Blockage of your digestive tract
    • History of changes to your digestive tract's anatomy
    • History of digestive tract problems
    • Taking medicines that can also cause blockage
  • Interference with X-rays
See more detailed risks and warnings
  • High iron levels
    • History of iron overload syndrome
  • Accidental iron overdose in children
    • Children under 6 years of age
  • Stomach problems
    • History of GI bleeding
    • History of inflammatory bowel disease
  • Interaction with antibiotics
    • Current use of doxycycline
    • Current use of ciprofloxacin
See more detailed risks and warnings