Compare Frova vs. Cafergot

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats migraine headaches.

Triptans are the first-choice to treat migraines. Frova (frovatriptan) works just as well as other triptans for migraines, but doesn't work for other types of headaches like cluster headaches.

Treats migraine headaches.

Cafergot (ergotamine / caffeine) can treat migraines, but you're more likely to have side effects.

Upsides
  • Frova (frovatriptan) is available in generic.
  • Unlike other similar medicines, you can take up to 3 tablets of Frova (frovatriptan) every 24 hours.
  • Frova (frovatriptan) is first choice of medicines for treatment of migraine headaches.
  • Cafergot (ergotamine / caffeine) works better than other medicines if your migraines usually last more than 2 days or if you have more frequent migraines.
Downsides
  • Available as an oral tablet only, which may be difficult to swallow during bad migraine attack.
  • Doesn't prevent migraines.
  • Doesn't work for other types of headaches like cluster headaches.
  • Not recommended for children under 18 years old.
  • Cafergot (ergotamine / caffeine) can't stop migraines from happening. They can only treat them.
  • Cafergot (ergotamine / caffeine) can only be used for migraines. It doesn't work for other types of headaches.
  • Smoking or using products that contain nicotine can make Cafergot (ergotamine / caffeine) less effective.
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Used for
Dosage forms
  • Pill
  • Pill
  • Suppository
Price
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Reviews
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Side effects
10possible side effects
  • Dizziness
    8%
  • Fatigue
    5%
  • Headache
    4%
  • Tingling or prickling sensation
    4%
  • Flushing
    4%
  • Dry mouth
    3%
  • Hot or cold sensation
    3%
  • Muscle pain
    3%
  • Indigestion
    2%
  • Chest pain
    2%
See more detailed side effects
The Cafergot (ergotamine / caffeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Heart attack
    • Heart disease
    • history of chest pain/angina
    • uncontrolled high blood pressure
  • Stroke
    • History of a stroke
  • Medication overuse headache
    • Using Frova (frovatriptan) for more than 2 to 3 days a week or 10 days a month
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
  • Increased blood pressure
    • Uncontrolled high blood pressure
  • Blood vessel issues
    • High blood pressure
    • history of stroke or heart attack
See more detailed risks and warnings
  • Heart and circulation problems
    • Overdosing Cafergot (ergotamine / caffeine)
    • Taking triptans (Imitrex, Axert, Maxalt, Amerge, Frova) for migraines
  • Dependency and withdrawal
    • Taking Cafergot (ergotamine / caffeine) regularly for months
  • Danger to fetus
See more detailed risks and warnings