Compare Genvoya vs. Complera

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT
Treats HIV infection.

Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication. It's one of the first choices used to treat HIV infections and contains a newer medication that's safer for your kidneys and bones.

Treats HIV infection

Complera (emtricitabine / rilpivirine / tenofovir) is a convenient 3-in-1 medication used to treat HIV infections.

Upsides
  • First-choice treatment for HIV infections.
  • One tablet contains four different HIV medications and is only taken once daily.
  • Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) has fewer side effects (headache, nausea, fatigue, diarrhea), and is safer on your kidneys and bones than Stribild.
  • Complera (emtricitabine / rilpivirine / tenofovir) combines three medications into one tablet, so it's easy to take.
  • Complera (emtricitabine / rilpivirine / tenofovir) might be an option for HIV treatment if other HIV drug combinations haven't worked for you.
  • There are drug assistance programs available either through the government (AIDS Drug Assistance Program aka. ADAP) or through the drug manufacturer which can help with drug costs and co-pays.
Downsides
  • Should be taken with food.
  • Can increase cholesterol levels.
  • Can interact with many other drugs.
  • Must be taken with a light meal which includes fat.
  • Cannot be taken with proton pump inhibitors (PPI) like Prilosec or Prevacid. If you need to take an acid reducer, try an antacid like calcium carbonate either 2 hours before or 4 hours after Complera (emtricitabine / rilpivirine / tenofovir). Drugs like Pepcid or Zantac (H2RAs) may also be an option, but these should be taken 12 hours before or 4 hours after Complera (emtricitabine / rilpivirine / tenofovir).
  • Not recommended for patients who have a significantly high level of viral cells or have a very low level of immune cells.
  • Not recommended for patients with kidney damage.
  • Can weaken your bones.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price
$2933.58
Find instant savings near you
Lowest price
$2670.55
Find instant savings near you
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
4possible side effects
  • Nausea
    10%
  • Diarrhea
    7%
  • Headache
    6%
  • Fatigue
    5%
See more detailed side effects
3possible side effects
  • Headache
    2%
  • Depressive disorders
    2%
  • Insomnia
    2%
See more detailed side effects
Risks and risk factors
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Worsening hepatitis B infection
    • Hepatitis B Virus infection
  • Kidney damage
    • History of kidney damage
    • Taking other medicines that can harm the kidneys
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Drug interactions
    • Taking medicines that interact with Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir)
See more detailed risks and warnings
  • Lactic acidosis | Enlarged, fatty liver
    • Liver disease
    • Women
    • Obesity
  • Cannot be used to treat Hepatitis B Virus (HBV)
    • Hepatitis B Virus infection
  • Mood and behavior changes
    • History of mental health problems
  • Decreased bone mineral density
    • History of bone fractures
    • Osteoporosis
  • Kidney damage
    • History of kidney damage
    • Concurrent use of drugs known to harm kidneys
  • Hypersensitivity (allergic) reactions
    • Prior severe allergic reaction to Complera (emtricitabine / rilpivirine / tenofovir) or any of its individual drug components.
See more detailed risks and warnings