Compare Genvoya vs. Odefsey
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats HIV infection.
Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication. It's one of the first choices used to treat HIV infections and contains a newer medication that's safer for your kidneys and bones.
Treats HIV infection
Odefsey (emtricitabine / rilpivirine / tenofovir) is a convenient 3-in-1 medication used to treat HIV infections. It's similar to Complera, but contains a newer HIV drug which has shown to cause less harmful effects on your kidneys and bones.
Upsides
- First-choice treatment for HIV infections.
- One tablet contains four different HIV medications and is only taken once daily.
- Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) has fewer side effects (headache, nausea, fatigue, diarrhea), and is safer on your kidneys and bones than Stribild.
- Odefsey (emtricitabine / rilpivirine / tenofovir) combines three medications into one tablet, so it's easy to take.
- Odefsey (emtricitabine / rilpivirine / tenofovir) is currently the smallest combination HIV tablet available.
- Odefsey (emtricitabine / rilpivirine / tenofovir) works similar to Complera, but is less likely to cause harmful side effects on your kidneys and bones.
- Odefsey (emtricitabine / rilpivirine / tenofovir) might be an option for HIV treatment if other HIV drug combinations haven't worked for you.
Downsides
- Should be taken with food.
- Can increase cholesterol levels.
- Can interact with many other drugs.
- Odefsey (emtricitabine / rilpivirine / tenofovir) has to be taken with a light meal.
- Cannot be taken with proton pump inhibitors (PPI) like Prilosec or Prevacid. If you need an acid reducer, try taking an antacid like calcium carbonate either 2 hours before or 4 hours after Odefsey (emtricitabine / rilpivirine / tenofovir). Drugs like Pepcid or Zantac (H2RAs) may also be an option, but these should be taken 12 hours before or 4 hours after Odefsey (emtricitabine / rilpivirine / tenofovir).
- Not recommended for patients who have a significantly high level of viral cells or have a very low level of immune cells.
- Can cause abnormal heart rhythm.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$3067.50
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$2792.40
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Side effects
8possible side effects
- Headache19%
- Depression19%
- Somnolence14%
- Nausea11%
- Dizziness8%
- Abdominal pain8%
- Vomiting6%
- Rash6%
Risks and risk factors
- Lactic acidosis | Enlarged, fatty liver
- Liver disease
- Women
- Obesity
- Worsening hepatitis B infection
- Hepatitis B Virus infection
- Kidney damage
- History of kidney damage
- Taking other medicines that can harm the kidneys
- Immune reconstitution syndrome
- HIV
- Exposure to other infections
- Start of a new HIV medication
- Change in HIV therapy
- Drug interactions
- Taking medicines that interact with Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir)
- Lactic acidosis | Enlarged, fatty liver
- Liver disease
- Women
- Obesity
- Worsening hepatitis B infection
- Hepatitis B Virus infection
- Mood and behavior changes
- History of mental health problems
- Bone loss/osteoporosis
- History of bone fractures
- Osteoporosis
- Kidney damage
- History of kidney damage
- Taking other medicines that can harm the kidneys
- Allergic reactions
- Prior severe allergic reaction to Odefsey (emtricitabine / rilpivirine / tenofovir) or any of its individual drug components.