Compare Genvoya vs. Sustiva
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats HIV infection.
Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) is a convenient 4-in-1 medication. It's one of the first choices used to treat HIV infections and contains a newer medication that's safer for your kidneys and bones.
Works with other medicines to treat HIV infection.
Sustiva (efavirenz) is one of the most widely used and effective components of an HIV medication regimen. However, it is not a first-line choice because it can have a lot of side effects.
Upsides
- First-choice treatment for HIV infections.
- One tablet contains four different HIV medications and is only taken once daily.
- Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir) has fewer side effects (headache, nausea, fatigue, diarrhea), and is safer on your kidneys and bones than Stribild.
- If first-line choices for HIV medications are not an option, Sustiva (efavirenz) would be a good alternative to consider.
- Only taken once daily.
- Sustiva (efavirenz) is available in combination tablets.
- Can be used in patients with mild to moderate kidney damage.
- Can be used in children who are at least 3 months old.
Downsides
- Should be taken with food.
- Can increase cholesterol levels.
- Can interact with many other drugs.
- Not suggested for women who plan on becoming pregnant.
- Many people exerience intolerable side effects (eg. insomnia, dizziness, abnormal dreams, confusion), which make it hard to take the medication regularly.
- Cannot be taken alone for treatment of HIV.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$3774.88
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$81.00
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Side effects
19possible side effects
- Skin rash16%
- Diarrhea14%
- Pain13%
- Nausea10%
- Dizziness9%
- Itching9%
- Fatigue8%
- Headache8%
- Insomnia7%
- Vomiting6%
- Trouble concentrating5%
- Depression5%
- Indigestion4%
- Anxiety4%
- Abnormal dreams3%
- Abdominal pain3%
- Sleepiness2%
- Nervousness2%
- Loss of appetite2%
Risks and risk factors
- Lactic acidosis | Enlarged, fatty liver
- Liver disease
- Women
- Obesity
- Worsening hepatitis B infection
- Hepatitis B Virus infection
- Kidney damage
- History of kidney damage
- Taking other medicines that can harm the kidneys
- Immune reconstitution syndrome
- HIV
- Exposure to other infections
- Start of a new HIV medication
- Change in HIV therapy
- Drug interactions
- Taking medicines that interact with Genvoya (elvitegravir / cobicistat / emtricitabine / tenofovir)
- Central nervous system (CNS) effects
- Starting Sustiva (efavirenz) for the first few weeks.
- Taking alcohol or other drugs that also affect your nervous system
- Fat redistribution
- HIV treatment
- Liver damage
- History of liver damage
- Alcohol intake
- Immune reconstitution syndrome
- HIV
- Exposure to other infections
- Start of a new HIV medication
- Change in HIV therapy
- Psychiatric effects
- History of mental illness
- History of substance abuse
- Rash
- History of severe skin reactions
- Children