Compare Geodon vs. fluphenazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Geodon (ziprasidone)

Prescription only

Prolixin (fluphenazine)

Prescription only
Helps control your thoughts and mood.

Geodon (ziprasidone) treats bipolar disorder and schizophrenia with fewer side effects than similar medications, but has a risk of abnormal heart rhythm.

3.4/ 5 average rating with 23 reviewsforGeodon
Treats schizophrenia and psychosis.

Prolixin (fluphenazine) can stabilize your mood. It is used to find the right dose for you before moving to a long-acting injection.

Upsides
  • Geodon (ziprasidone) effectively stabilizes mood in schizophrenia and bipolar disorder.
  • Compared to other antipsychotics, this drug has a lower risk of weight gain, high blood sugars, and high cholesterol.
  • Geodon (ziprasidone) capsule is available as a generic.
  • Available as a daily pill for long-term treatment.
  • Good at stabilizing your mood.
  • Available in several oral and injectable forms, including a long-acting injection that is taken less frequently.
Downsides
  • It may take several weeks before you feel the full effects of Geodon (ziprasidone).
  • Might not be a good option if you have a history of heart problems.
  • You will need to get blood tests before you start taking Geodon (ziprasidone) to make sure you're healthy enough to take it.
  • People who are also taking diuretics will need regular blood tests while on Geodon (ziprasidone).
  • Can make you sensitive to the sun.
  • Can affect how your body regulates your temperature.
  • Can make it difficult for you to control your movements if you've been on Prolixin (fluphenazine) for a while.
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Used for
Dosage forms
  • Pill
  • Pill
  • Liquid
  • Injection
Price
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Reviews
23 reviews so far
43%
saidit'sworth it
43%
saiditworked well
30%
saidit'sa big hassle

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Side effects
23possible side effects
  • Sleepiness
    31%
  • Movement problems
    31%
  • Headache
    18%
  • Dizziness
    16%
  • Nausea
    10%
  • Restlessness
    10%
  • Weakness
    6%
  • Abnormal vision
    6%
  • Diarrhea
    5%
  • Dry mouth
    5%
  • Vomiting
    5%
  • Anxiety
    5%
  • Accidental injury
    4%
  • Increased salivation
    4%
  • High blood pressure
    3%
  • Tongue swelling
    3%
  • Sore throat
    3%
  • Difficulty swallowing
    2%
  • Muscle pain
    2%
  • Loss of sensation
    2%
  • Speech disorder
    2%
  • Shortness of breath
    2%
  • Itchy, red skin
    2%
See more detailed side effects
The Prolixin (fluphenazine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
  • Heart problems
    • History of heart problems
    • Taking other drugs that also cause heart rhythm changes
    • Low potassium
    • Low magnesium
  • Neuroleptic malignant syndrome (NMS)
  • Abnormal and involuntary muscle movements
    • Taking Geodon (ziprasidone) in higher doses or for a long time
    • Elderly women
  • Dizziness and falls
    • Dehydration
    • Taking blood pressure medications
    • History of heart disease
See more detailed risks and warnings
  • Increased risk of death
    • People over 65 with dementia and psychosis
  • Difficulty controlling movements
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Low white blood cell count
See more detailed risks and warnings