Compare Gilenya vs. Aubagio

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Gilenya (fingolimod)

Prescription only

Aubagio (Teriflunomide)

Prescription only
Treats relapsing forms of multiple sclerosis.

Gilenya (fingolimod) reduces the number of flare-ups, new brain lesions, and physical changes in relapsing MS, but it has many side effects.

3.0/ 5 average rating with 57 reviewsforGilenya
Treats relapsing types of multiple sclerosis.

Aubagio (Teriflunomide) significantly improves many symptoms of multiple sclerosis (MS), which may not be seen with some other MS medications.

2.5/ 5 average rating with 23 reviewsforAubagio
Upsides
  • Gilenya (fingolimod) is the first once-daily pill you can take for relapsing forms of MS.
  • Gilenya (fingolimod) lowers relapse rates and the number of new MS lesions better than the leading injectable.
  • Gilenya (fingolimod) takes up to 2 months to leave your body, which is much shorter than another oral medication Aubagio(teriflunomide), which can take up to 2 years.
  • Aubagio (Teriflunomide) can help reduce the number of flare-ups, slow physical changes, and decrease new brain lesions.
  • Aubagio (Teriflunomide) comes as a pill instead of an injection.
  • You only need to take Aubagio (Teriflunomide) once a day, with or without food.
Downsides
  • Gilenya (fingolimod) takes up to 2 months to leave your body – much longer than a similar medication, Tecfidera (dimethyl fumarate), which takes only a few hours.If you haven't had chickenpox or been vaccinated for it yet, you'll need to get the vaccine at least 1 month before starting Gilenya (fingolimod).
  • Gilenya (fingolimod) might not be a good choice if you have kidney, liver, or heart problems.
  • If you've stopped taking Gilenya (fingolimod) for 2 weeks or more, you'll have to take your first dose at your doctor's office when restarting.
  • Can cause temporary hair loss but it will grow back after stopping.
  • You'll need blood tests before and during treatment to make sure you don't develop any liver problems while taking Aubagio (Teriflunomide).
  • Aubagio (Teriflunomide) may stay in your blood for up to 2 years after taking it, so it is important to discuss a plan with your doctor in case it's not the right medication for you.
  • You can't take Aubagio (Teriflunomide) if you're pregnant, have severe liver damage, or are currently taking Arava (leflunomide).
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Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price
$8136.94
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Reviews
57 reviews so far
42%
saidit'sworth it
30%
saiditworked well
30%
saidit'sa big hassle

Have you used Gilenya (fingolimod)?

Leave a review
23 reviews so far
43%
saidit'sworth it
26%
saiditworked well
30%
saidit'sa big hassle

Have you used Aubagio (Teriflunomide)?

Leave a review
Side effects
22possible side effects
  • Headache
    25%
  • Abnormal liver blood tests
    15%
  • Nausea
    13%
  • Diarrhea
    13%
  • Cough
    12%
  • Flu infection
    11%
  • Sinus infection
    11%
  • Stomach pain
    11%
  • Back pain
    10%
  • Pain in arms or legs
    10%
  • Shortness of breath
    9%
  • Bronchitis
    8%
  • High blood pressure
    8%
  • Migraine
    6%
  • Blurred vision
    4%
  • Low blood pressure
    3%
  • Hair loss
    3%
  • Herpes viral infections
    2%
  • Fungal skin infection
    2%
  • Weakness
    2%
  • Scaly skin
    2%
  • Low white blood cells
    2%
See more detailed side effects
9possible side effects
  • Headache
    18%
  • Abnormal liver enzymes
    13%
  • Diarrhea
    13%
  • Hair loss
    10%
  • Nausea
    8%
  • Burning or prickling sensation in hands, arms, legs, or feet
    8%
  • Joint pain
    8%
  • Low white blood cells
    4%
  • High blood pressure
    3%
See more detailed side effects
Risks and risk factors
  • Heart problems
    • Taking other medicines that slow heart rate
    • History of heart problems
  • Serious infections
    • Taking other immunosuppressant medicines
    • Age 60 or older
    • Weak immune system
  • Eye problems
    • Diabetes
    • History of eye inflammation (uveitis)
  • Risk to fetus
    • Women of childbearing age
  • Breathing problems
    • History of lung problems
  • Liver problems
    • History of liver problems
See more detailed risks and warnings
  • Liver problems
    • Taking medicines that affect your liver or cause liver injury
  • Harm to unborn baby
  • Slow elimination from body
  • Serious skin reactions
  • Numbness in extremities (hands and feet)
    • Age 60 or older
    • Taking medicines that are toxic to the nervous system
    • Diabetes
  • Risk of serious infections
    • Taking other drugs that weaken your immune system
    • Age 60 or older
    • Weak immune system
See more detailed risks and warnings