Compare Glucotrol vs. glyburide
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Glucotrol (glipizide) is an effective medicine for lowering blood sugar, but it can cause your blood sugar level to be too low so you must always carry some form of sugar with you that can be readily used.
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3.2/ 5 average rating with 332 reviewsforGlucotrol
Lowers blood sugar.
Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
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3.3/ 5 average rating with 110 reviewsforglyburide
Upsides
- Lowers A1c levels by 1-2%.
- Glucotrol (glipizide) is an oral medicine so it might be a good alternative for those who don't like injections.
- Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
- Okay to use by people with kidney problems.
- Available as a generic form and is relatively cheap.
- Available as an oral tablet.
- Lowers your A1c (average blood sugar over time) up to 2%.
- Available in generic version.
- Available in single pill combination with other anti-diabetic medicines.
Downsides
- Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
- While taking Glucotrol (glipizide), your blood sugars should be checked 2 to 5 times a week, but less often once you are on a stable dose.
- Can cause mild weight gain of 2-3lb.
- Might lose its effectiveness over time.
- Needs to be taken 30 minutes before a meal for it to be most effective.
- More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
- You will have to check your blood sugar often when you first start taking it.
- Can cause weight gain (about 2 to 3 pounds).
- Not ideal for elderly or those with poor kidney function.
- May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
Used for
Dosage forms
- Pill
- Extended release pill
- Pill
Price
Lowest price
$9.00
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$16.73
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Reviews
332 reviews so far
50%
saidit'sworth it
32%
saiditworked well
19%
saidit'sa big hassle
Have you used Glucotrol (glipizide)?
Leave a review110 reviews so far
45%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle
Have you used Diabeta (glyburide)?
Leave a reviewSide effects
9possible side effects
- Dizziness7%
- Diarrhea5%
- Nervousness4%
- Tremor4%
- Low blood sugar3%
- Constipation3%
- Passing gas3%
- Nausea3%
- Headache2%
Risks and risk factors
- Serious heart problems
- Low blood sugar
- Skipping meals or having inconsistent meal times
- Drinking alcohol
- Using other blood sugar-lowering medicine
- People age 60 or older
- Those with kidney and/or liver problems
- Severe allergic reaction
- History of allergy to sulfa-containing medicine
- Kidney and liver disease
- Those with kidney and/or liver disease
- Breakdown of red blood cells
- People with G6PD deficiency
- Low blood sugar
- Over age 65
- Kidney problems
- Use of other blood sugar lowering medicines
- Alcohol
- Intense physical activity
- Severe allergic reactions
- History of sulfa allergies