Compare glyburide vs. Humalog
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
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3.3/ 5 average rating with 110 reviewsforglyburide
Lowers blood sugar.
Humalog (insulin lispro) is a fast-acting insulin that controls blood sugar around meal times.
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3.7/ 5 average rating with 280 reviewsforHumalog
Upsides
- Available as an oral tablet.
- Lowers your A1c (average blood sugar over time) up to 2%.
- Available in generic version.
- Available in single pill combination with other anti-diabetic medicines.
- Humalog (insulin lispro) is the most effective medication for lowering your blood sugar.
- Works quickly to control your sugar levels after meals.
- Dose can be easily adjusted to create a regimen that's tailored to your body's needs.
- Humalog (insulin lispro) can be used even if you have liver or kidney problems, unlike other anti-diabetic medications.
Downsides
- More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
- You will have to check your blood sugar often when you first start taking it.
- Can cause weight gain (about 2 to 3 pounds).
- Not ideal for elderly or those with poor kidney function.
- May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
- You have to take Humalog (insulin lispro) by injection.
- Humalog (insulin lispro) is likely to cause moderate weight gain (around 4 to 6 pounds).
- There is a higher risk for episodes of low blood sugar compared to other anti-diabetic medications.
- Effects do not last long enough to control your blood sugar for a whole day.
Used for
Dosage forms
- Pill
- Injection
Price
Lowest price
$27.88
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$142.55
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Reviews
110 reviews so far
45%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle
Have you used Diabeta (glyburide)?
Leave a review280 reviews so far
64%
saidit'sworth it
50%
saiditworked well
16%
saidit'sa big hassle
Have you used Humalog (insulin lispro)?
Leave a reviewSide effects
The Humalog (insulin lispro) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Low blood sugar
- Over age 65
- Kidney problems
- Use of other blood sugar lowering medicines
- Alcohol
- Intense physical activity
- Severe allergic reactions
- History of sulfa allergies
- Life-threatening low blood sugar (hypoglycemia)
- Insulin dose too high
- Use of other blood sugar lowering medications
- Poor injection techniques
- Complications due to low potassium
- Use of medications that lower potassium
- Current electrolyte imbalance
- Severe allergic reactions
- Allergy to insulin