Compare glyburide vs. Janumet
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
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3.3/ 5 average rating with 110 reviewsforglyburide
Lowers your blood sugar.
Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.
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3.4/ 5 average rating with 79 reviewsforJanumet
Upsides
- Available as an oral tablet.
- Lowers your A1c (average blood sugar over time) up to 2%.
- Available in generic version.
- Available in single pill combination with other anti-diabetic medicines.
- This 2-in-1 combination can lower the number of pills you have to take daily.
- Lowers A1c (average blood sugar over time) up to 2.5%.
- Available in extended and immediate release forms to allow better control of your blood sugar.
- Doesn't increase your appetite unlike other anti-diabetic medicines.
- Does not cause hypoglycemia or very low blood sugar.
Downsides
- More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
- You will have to check your blood sugar often when you first start taking it.
- Can cause weight gain (about 2 to 3 pounds).
- Not ideal for elderly or those with poor kidney function.
- May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
- Available as brand name only and may be expensive.
- Metformin component usually causes upset stomach.
- Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
- Not appropriate for those with poor kidney function.
Used for
Dosage forms
- Pill
- Pill
- Extended release
Price
Lowest price
$27.88
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$490.99
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Reviews
110 reviews so far
45%
saidit'sworth it
34%
saiditworked well
21%
saidit'sa big hassle
Have you used Diabeta (glyburide)?
Leave a review79 reviews so far
46%
saidit'sworth it
38%
saiditworked well
15%
saidit'sa big hassle
Have you used Janumet (sitagliptin / metformin)?
Leave a reviewSide effects
5possible side effects
- Low blood sugar16%
- Diarrhea8%
- Upper respiratory tract infection6%
- Headache6%
- Abdominal pain2%
Risks and risk factors
- Low blood sugar
- Over age 65
- Kidney problems
- Use of other blood sugar lowering medicines
- Alcohol
- Intense physical activity
- Severe allergic reactions
- History of sulfa allergies
- Excess lactic acid in the blood
- Kidney problems
- Liver problems
- Congestive heart failure
- Using contrast dye for procedures
- Surgery
- Alcohol use
- Low vitamin B12 levels
- Inflammation of the pancreas
- Serious allergic reactions