Compare Haldol vs. loxapine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Haldol (haloperidol)

Prescription only

Loxitane (loxapine)

Prescription only
Helps control your thoughts, calm agitation, and stabilize your mood.

Haldol (haloperidol) is less likely to cause weight gain and sedation, but more likely to cause movement disorders compared to other antipsychotics.

3.1/ 5 average rating with 50 reviewsforHaldol
Treats schizophrenia.

Loxitane (loxapine) is not recommended as a first choice medicine for treatment of schizophrenia, but it can be good if other medicines haven't worked because of bad side effects.

Upsides
  • Haldol (haloperidol) is available in a cheap, generic version.
  • A monthly extended-release injection allows for more convenient dosing than a daily pill.
  • Loxitane (loxapine) can be used to control schizophrenia if other medicines haven't worked because you don't like their side effects.
  • Loxitane (loxapine) is available as a generic.
Downsides
  • Haldol (haloperidol) is an older medicine and has a lot more problematic side effects compared to newer antipsychotics.
  • You might need routine blood tests and regular check-ups to make sure the medicine is working for you.
  • Loxitane (loxapine) is not recommended as a first choice for treating schizophrenia because it's more likely to cause trouble with controlling movements.
  • Loxitane (loxapine) can stop vomiting, so it can be difficult to tell if someone's overdosed on drugs.
  • Loxitane (loxapine) can raise heart rate and lower blood pressure.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Injection
  • Pill
Price
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Reviews
50 reviews so far
38%
saidit'sworth it
42%
saiditworked well
34%
saidit'sa big hassle

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Side effects
The Haldol (haloperidol) FDA package insert doesn’t have numbers about how common side effects are.
The Loxitane (loxapine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Blood disorders
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Shaking and restlessness
  • Driving impairment
    • Drinking alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Higher risk of death
    • People age 65 and older with dementia and psychosis
  • Difficulty controlling movements
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Seizures
    • History of seizures
  • Vision changes
See more detailed risks and warnings