Compare Haldol vs. Rexulti

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Haldol (haloperidol)

Prescription only

Rexulti (brexpiprazole)

Prescription only
Helps control your thoughts, calm agitation, and stabilize your mood.

Haldol (haloperidol) is less likely to cause weight gain and sedation, but more likely to cause movement disorders compared to other antipsychotics.

3.1/ 5 average rating with 50 reviewsforHaldol
Helps improve your mood and control your thoughts.

Rexulti (brexpiprazole) is an option for people with depression or schizophrenia but it can be more expensive than other medicines.

Upsides
  • Haldol (haloperidol) is available in a cheap, generic version.
  • A monthly extended-release injection allows for more convenient dosing than a daily pill.
  • Rexulti (brexpiprazole) does not cause as much weight gain as other similar medications.
  • Fewer side effects compared to other similar medications.
Downsides
  • Haldol (haloperidol) is an older medicine and has a lot more problematic side effects compared to newer antipsychotics.
  • You might need routine blood tests and regular check-ups to make sure the medicine is working for you.
  • Avaliable only as brand name and can be more expensive than other options. However, there may be programs to help with co-pays.
  • Rexulti (brexpiprazole) can cause restlessness, especially when you take higher doses and after a long period of time.
  • Can increase your cholesterol, blood sugar, and cause weight gain.
  • Elderly patients with dementia should not take Rexulti (brexpiprazole).
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Used for
Dosage forms
  • Pill
  • Liquid
  • Injection
  • Pill
Price
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Reviews
50 reviews so far
38%
saidit'sworth it
42%
saiditworked well
34%
saidit'sa big hassle

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Side effects
The Haldol (haloperidol) FDA package insert doesn’t have numbers about how common side effects are.
13possible side effects
  • Agitation
    9%
  • Weight gain
    7%
  • Headache
    7%
  • Sleepiness
    5%
  • Common cold
    4%
  • Tremors
    4%
  • Fatigue
    3%
  • Increased appetite
    3%
  • Dizziness
    3%
  • Anxiety
    3%
  • Restlessness
    3%
  • Constipation
    2%
  • Decreased cortisol
    2%
See more detailed side effects
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Blood disorders
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Shaking and restlessness
  • Driving impairment
    • Drinking alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
    • Under 24 years of age
  • Neuroleptic malignant syndrome
  • Difficulty controlling movements
    • Women over age 65
  • Higher blood sugar and cholesterol, and weight gain
    • People with diabetes
    • People with high cholesterol
  • Risk of infection
See more detailed risks and warnings