Compare Haldol vs. thioridazine

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Haldol (haloperidol)

Prescription only

Mellaril (thioridazine)

Prescription only
Helps control your thoughts, calm agitation, and stabilize your mood.

Haldol (haloperidol) is less likely to cause weight gain and sedation, but more likely to cause movement disorders compared to other antipsychotics.

3.1/ 5 average rating with 50 reviewsforHaldol
Treats schizophrenia.

Taking Mellaril (thioridazine) is one of many options to treat schizophrenia if other medicines haven't worked, but there are some side effects which can be dangerous.

  • Haldol (haloperidol) is available in a cheap, generic version.
  • A monthly extended-release injection allows for more convenient dosing than a daily pill.
  • Available in generic.
  • Compared to other similar medicines, Mellaril (thioridazine) is less likely to cause problems controlling your movements.
  • Haldol (haloperidol) is an older medicine and has a lot more problematic side effects compared to newer antipsychotics.
  • You might need routine blood tests and regular check-ups to make sure the medicine is working for you.
  • Mellaril (thioridazine) is only recommended for schizophrenia if other medicines haven't worked because the side effects can be very dangerous.
  • You have to take Mellaril (thioridazine) numerous times a day which can make it hard to remember.
  • Mellaril (thioridazine) can interfere with your heartbeat, so your doctor might have you do annual tests with your heart to make sure it's healthy.
Used for
Dosage forms
  • Pill
  • Liquid
  • Injection
  • Pill
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Side effects
The Haldol (haloperidol) FDA package insert doesn’t have numbers about how common side effects are.
The Mellaril (thioridazine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Increased risk of death
    • Elderly patients with dementia
  • Blood disorders
  • Neuroleptic malignant syndrome
  • Heart problems
    • History of heart problems
    • Drug interactions
  • Shaking and restlessness
  • Driving impairment
    • Drinking alcohol
    • Taking other medicines that make you less alert
See more detailed risks and warnings
  • Problems with the heartbeat
    • History of heartbeat problems
    • Taking medicines for depression
    • Taking beta blockers
  • Increased risk of death in elderly people with dementia
    • People older than 65 years with dementia and psychosis
  • Difficulty controlling movements
    • Long-term use of Mellaril (thioridazine)
  • Neuroleptic malignant syndrome
    • Taking antipsychotic medications
  • Sleepiness and risk of falls
    • Drinking alcohol or taking narcotics
  • Decreased white blood cells
    • History of low white blood cells
See more detailed risks and warnings