Compare Humalog vs. Janumet
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Humalog (insulin lispro) is a fast-acting insulin that controls blood sugar around meal times.
●●●●●
3.7/ 5 average rating with 280 reviewsforHumalog
Lowers your blood sugar.
Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.
●●●●●
3.4/ 5 average rating with 79 reviewsforJanumet
Upsides
- Humalog (insulin lispro) is the most effective medication for lowering your blood sugar.
- Works quickly to control your sugar levels after meals.
- Dose can be easily adjusted to create a regimen that's tailored to your body's needs.
- Humalog (insulin lispro) can be used even if you have liver or kidney problems, unlike other anti-diabetic medications.
- This 2-in-1 combination can lower the number of pills you have to take daily.
- Lowers A1c (average blood sugar over time) up to 2.5%.
- Available in extended and immediate release forms to allow better control of your blood sugar.
- Doesn't increase your appetite unlike other anti-diabetic medicines.
- Does not cause hypoglycemia or very low blood sugar.
Downsides
- You have to take Humalog (insulin lispro) by injection.
- Humalog (insulin lispro) is likely to cause moderate weight gain (around 4 to 6 pounds).
- There is a higher risk for episodes of low blood sugar compared to other anti-diabetic medications.
- Effects do not last long enough to control your blood sugar for a whole day.
- Available as brand name only and may be expensive.
- Metformin component usually causes upset stomach.
- Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
- Not appropriate for those with poor kidney function.
Used for
Dosage forms
- Injection
- Pill
- Extended release
Price
Lowest price
$144.20
Find instant savings near youLowest price
$549.57
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
280 reviews so far
64%
saidit'sworth it
50%
saiditworked well
16%
saidit'sa big hassle
Have you used Humalog (insulin lispro)?
Leave a review79 reviews so far
46%
saidit'sworth it
38%
saiditworked well
15%
saidit'sa big hassle
Have you used Janumet (sitagliptin / metformin)?
Leave a reviewSide effects
The Humalog (insulin lispro) FDA package insert doesn’t have numbers about how common side effects are.
5possible side effects
- Low blood sugar16%
- Diarrhea8%
- Upper respiratory tract infection6%
- Headache6%
- Abdominal pain2%
Risks and risk factors
- Life-threatening low blood sugar (hypoglycemia)
- Insulin dose too high
- Use of other blood sugar lowering medications
- Poor injection techniques
- Complications due to low potassium
- Use of medications that lower potassium
- Current electrolyte imbalance
- Severe allergic reactions
- Allergy to insulin
- Excess lactic acid in the blood
- Kidney problems
- Liver problems
- Congestive heart failure
- Using contrast dye for procedures
- Surgery
- Alcohol use
- Low vitamin B12 levels
- Inflammation of the pancreas
- Serious allergic reactions