Compare Humira vs. Taclonex

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Calms down the immune system.

Humira (adalimumab) is good for treating many autoimmune conditions, but it can also cause serious side effects.

3.6/ 5 average rating with 182 reviewsforHumira
Treats plaque psoriasis.

Taclonex (calcipotriene / betamethasone) is effective at treating mild to moderate psoriasis but can cause skin irritation.

  • Humira (adalimumab) is effective in reducing symptoms in all of its approved indications.
  • You can give yourself Humira (adalimumab) on your own at home rather than visiting a clinic or hospital.
  • Humira (adalimumab) treats many different autoimmune conditions.
  • Available in a single-use pen (Humira Pen) that may be more convenient and easier for some people to use.
  • Only apply Taclonex (calcipotriene / betamethasone) once a day.
  • Contains both betamethasone and calcipotriene together so you don't have to use two separate products.
  • Betamethasone and calcipotriene together is more effect than one product alone.
  • Is the primary treatment for mild to moderate psoriasis.
  • Ointment form is available as a generic.
  • Not first-choice treatment for rheumatoid arthritis.
  • Humira (adalimumab) is an injection and not an oral medication.
  • Humira (adalimumab) is expensive because there's no generic available yet.
  • Humira (adalimumab) lowers your ability to fight infection and in some cases can cause serious life-threatening illness. The risk is greater if you take other drugs that lower your immune system, have an active infection, diabetes, or had tuberculosis (TB) in the past.
  • You'll need to properly dispose of the needle, syringes, or Pen in a sharps container.
  • Humira (adalimumab) needs to be refrigerated until you use it, so if you're traveling, you'll need to carry it in a cooler with an ice pack.
  • You will need stronger medication if you have severe psoriasis.
  • May be more expensive than other topical medicines.
  • Can cause you to be senstive to natural and artificial sunlight.
  • Suspension and foam forms of Taclonex (calcipotriene / betamethasone) are not available as a generic.
Used for
Dosage forms
  • Injection
  • Ointment
  • Suspension
  • Foam
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182 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

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Side effects
14possible side effects
  • Upper airway infection
  • Headache
  • Rash
  • Sinus infection
  • Nausea
  • Injection site reactions
  • Urinary tract infection
  • Flu syndrome
  • Stomach pain
  • High cholesterol
  • Back pain
  • Blood in urine
  • Abnormal liver tests
  • High blood pressure
See more detailed side effects
5possible side effects
  • Itching
  • Headache
  • Psoriasis
  • Common cold
  • Skin thinning
See more detailed side effects
Risks and risk factors
  • Serious infections
    • Taking other immunosuppressant medications such as Kineret or Orencia
    • Age 65 or older
    • Active, chronic, or recurrent infection
    • Comorbidities
  • Cancers
    • Taking other immunosuppressant medications, such as azathiprine or 6-mercaptopurine, at the same time as Humira (adalimumab)
    • History of malignancy
    • Adolescent age
    • COPD with significant smoking history
  • Serious allergic reactions
  • Heart problems
    • History of heart failure
  • Nervous system effects
    • Preexisting or recently acquired neurologic condition
  • Lower blood cell counts
See more detailed risks and warnings
  • Raised calcium levels
    • Problems with calcium metabolism
  • Adrenal gland problems
    • High potency corticosteroids
    • Large treatment surface areas
    • Long-term use
    • Using more than one corticosteroid product
    • Liver failure
    • Young age
    • Altered skin barrier
    • Using occlusive dressings
  • Allergic skin reaction
  • Skin irritation
  • Sunburn
    • Sun exposure
See more detailed risks and warnings