Compare hydrochlorothiazide vs. Dutoprol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Removes water from the body, which lowers blood pressure.

Microzide (hydrochlorothiazide (HCTZ)) is a well-tolerated water pill that's often the first-choice treatment for mild high blood pressure.

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3.3/ 5 average rating with 139 reviewsforhydrochlorothiazide
Lowers blood pressure.

Dutoprol (Metoprolol Succinate / Hydrochlorothiazide) helps lower blood pressure by working in two different ways in your body. It's good for stubbornly high blood pressure.

Upsides
  • Does a good job getting rid of extra fluids in your body by making you urinate more.
  • A first-choice blood pressure treatment. Works especially well for people of African descent.
  • Lowers the risk of heart attack and stroke.
  • Good option if you have high blood pressure and heart failure.
  • Most people have very few side effects from Microzide (hydrochlorothiazide (HCTZ)).
  • Can be good for patients with osteoporosis since it raises the body's level of calcium.
  • Lowers the risk of heart attack and stroke.
  • Combines the benefits of two blood pressure-lowering medicines in a single pill.
  • Helpful in getting rid of extra fluids in your body.
Downsides
  • Makes you urinate more often.
  • Microzide (hydrochlorothiazide (HCTZ)) doesn't work well in people with severe kidney problems.
  • It can increase the risk of gout attacks in people with poor kidney function or a history of gout.
  • People with a sulfa allergy may be allergic to Microzide (hydrochlorothiazide (HCTZ)).
  • Not the first choice to lower blood pressure.
  • Brand only, can be more expensive.
  • Can make you urinate more often and feel out of breath during physical activities, which may not go away.
  • Can hide symptoms of low blood sugar. Be careful if you're diabetic.
  • Forgetting to take the medicine or stopping it suddenly can cause a heart attack.
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Used for
Dosage forms
  • Pill
  • Pill
Price
Lowest price
$107.46
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Lowest price
$225.07
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Reviews
139 reviews so far
47%
saidit'sworth it
31%
saiditworked well
16%
saidit'sa big hassle

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Side effects
The Microzide (hydrochlorothiazide (HCTZ)) FDA package insert doesn’t have numbers about how common side effects are.
5possible side effects
  • Nasopharyngitis
    3%
  • Fatigue
    3%
  • Dizziness
    3%
  • Any side effect
    3%
  • Back pain
    2%
See more detailed side effects
Risks and risk factors
  • Dehydration and electrolyte imbalance
    • Current electrolyte imbalance
    • Lower kidney function
    • Dehydration
  • Severe allergic reactions
    • History of sulfa allergies
  • Gout
    • History of gout
    • Current kidney problems
  • Vision problems
    • History of sulfa or penicillin allergies
  • Higher blood sugars
    • Diabetes
See more detailed risks and warnings
  • Heart problems
    • Sudden discontinuation of medicine
  • Trouble breathing (bronchospastic disease)
    • History of asthma
  • Low blood sugar unawareness
    • History of diabetes
  • Low heart rate (bradycardia)
    • Age 65 years or older
    • Using other medicine(s) that slows the heart
  • Dehydration and electrolyte imbalance
    • Current electrolyte imbalance
  • Gout
    • History of gout
    • Current kidney problems
See more detailed risks and warnings
Learn more about Microzide (hydrochlorothiazide (HCTZ))
Learn more about Dutoprol (Metoprolol Succinate / Hydrochlorothiazide)