Compare ibuprofen vs. Acetaminophen with codeine
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relieves pain, fever, and swelling.
Advil (ibuprofen) works well for treating fever, inflammation, and a variety of mild to moderate pain conditions, but it doesn't last as long as other NSAIDs.
●●●●●
4.0/ 5 average rating with 892 reviewsforibuprofen
Treats mild to moderate pain.
Acetaminophen with codeine (acetaminophen / codeine) is a good option to treat pain when over-the-counter medicines aren't enough, but don't take too much acetaminophen (Tylenol) since it can hurt your liver.
●●●●●
3.7/ 5 average rating with 581 reviewsforAcetaminophen with codeine
Upsides
- Advil (ibuprofen) is effective for treating fever, pain, and inflammation.
- Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
- Advil (ibuprofen) is generally safe to use, cheap, and available over-the-counter.
- Advil (ibuprofen) causes less stomach problems than its alternatives.
- It comes in different flavored liquid forms that makes it easy for children to take.
- Combination pain medicine with an opioid component (codeine) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relief in a single pill.
- Provides quick relief for mild to moderate pain.
- Good for as-needed pain and control.
- Generally well tolerated, especially if taken with food to lower risk of stomach upset.
- Lower rates of misuse compared to pure opioid medicines.
Downsides
- Advil (ibuprofen) doesn't last as long as other NSAIDs, so you need to take it a few times a day to get relief of your symptoms.
- It needs to be taken with food or millk to avoid getting an upset stomach.
- Advil (ibuprofen) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
- It can cause serious complications like stomach bleeding and kidney problems if taken for a long period of time.
- Like all NSAIDs, Advil (ibuprofen) can raise your risk of getting blood clots, a heart attack, or stroke.
- Dizziness and drowsiness is common, but your body may adjust.
- Many people get constipated taking Acetaminophen with codeine (acetaminophen / codeine).
- All opioid containing medicines have the risk of addiction and withdrawal when used long-term.
- Acetaminophen (Tylenol) has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful since many over-the-counter medicines also have acetaminophen.
Used for
Dosage forms
- Pill
- Chewable tablet
- Suspension
- Pill
- Liquid
Price
Lowest price
$6.00
Find instant savings near youLowest price
$8.52
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
892 reviews so far
88%
saidit'sworth it
52%
saiditworked well
4%
saidit'sa big hassle
Have you used Advil (ibuprofen)?
Leave a review581 reviews so far
69%
saidit'sworth it
41%
saiditworked well
9%
saidit'sa big hassle
Have you used Acetaminophen with codeine (acetaminophen / codeine)?
Leave a reviewSide effects
The Advil (ibuprofen) FDA package insert doesn’t have numbers about how common side effects are.
The Acetaminophen with codeine (acetaminophen / codeine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Heart attack and stroke
- History of heart problems
- Taking Advil (ibuprofen) for a long period of time
- Stomach bleeding
- History of stomach bleeding
- Age 60 or older
- Taking aspirin, other NSAIDs, or blood thinners
- Drinking more than 3 alcoholic beverages a day
- Smoking
- Taking the medicine for a long period of time
- Severe allergic reaction
- Asthma
- Nasal polyps
- Aspirin allergy
- NSAID allergy
- Kidney damage
- Kidney disease
- Heart failure
- Liver disease
- Taking certain high blood pressure medications
- Age 60 or older
- Taking the medicine for a long period of time
- Harm to fetus (unborn baby)
- Women who want to or can become pregnant
- Pregnant women
- Liver failure and death
- Alcohol use
- Taking over-the-counter medicines with acetaminophen
- History of liver disease
- High risk to children
- Use with other CNS depressants
- Use with alcohol
- Use with benzodiazepines
- Use with other opiates
- Severe allergic reaction