Compare ibuprofen vs. Percocet
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relieves pain, fever, and swelling.
Advil (ibuprofen) works well for treating fever, inflammation, and a variety of mild to moderate pain conditions, but it doesn't last as long as other NSAIDs.
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4.0/ 5 average rating with 892 reviewsforibuprofen
Treats moderate to severe pain.
Percocet (Oxycodone / Acetaminophen) is the strongest prescription combination pain medicine for as needed pain relief, but make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.
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3.8/ 5 average rating with 1399 reviewsforPercocet
Upsides
- Advil (ibuprofen) is effective for treating fever, pain, and inflammation.
- Good for relieving pain due to common conditions like menstrual cramps, toothaches, backaches, and sports-related injuries.
- Advil (ibuprofen) is generally safe to use, cheap, and available over-the-counter.
- Advil (ibuprofen) causes less stomach problems than its alternatives.
- It comes in different flavored liquid forms that makes it easy for children to take.
- Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
- Provides quick relief for moderate to severe pain to improve quality of life.
- Generally considered stronger than Norco or other combination pain medicine for treating pain.
- Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
- Lower rates of misuse compared to pure opioid medicines.
- Can help you fall asleep easier.
Downsides
- Advil (ibuprofen) doesn't last as long as other NSAIDs, so you need to take it a few times a day to get relief of your symptoms.
- It needs to be taken with food or millk to avoid getting an upset stomach.
- Advil (ibuprofen) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
- It can cause serious complications like stomach bleeding and kidney problems if taken for a long period of time.
- Like all NSAIDs, Advil (ibuprofen) can raise your risk of getting blood clots, a heart attack, or stroke.
- Dizziness and drowsiness is common, but your body may adjust.
- Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Percocet if you need.
- All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
- The non-opioid part of Percocet, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
- Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
- Avoid alcohol.
Used for
Dosage forms
- Pill
- Chewable tablet
- Suspension
- Pill
- Oral solution
Price
Lowest price
$7.10
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$222.96
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Reviews
892 reviews so far
88%
saidit'sworth it
52%
saiditworked well
4%
saidit'sa big hassle
Have you used Advil (ibuprofen)?
Leave a review1399 reviews so far
70%
saidit'sworth it
49%
saiditworked well
15%
saidit'sa big hassle
Have you used Percocet (Oxycodone / Acetaminophen)?
Leave a reviewSide effects
The Advil (ibuprofen) FDA package insert doesn’t have numbers about how common side effects are.
The Percocet (Oxycodone / Acetaminophen) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Heart attack and stroke
- History of heart problems
- Taking Advil (ibuprofen) for a long period of time
- Stomach bleeding
- History of stomach bleeding
- Age 60 or older
- Taking aspirin, other NSAIDs, or blood thinners
- Drinking more than 3 alcoholic beverages a day
- Smoking
- Taking the medicine for a long period of time
- Severe allergic reaction
- Asthma
- Nasal polyps
- Aspirin allergy
- NSAID allergy
- Kidney damage
- Kidney disease
- Heart failure
- Liver disease
- Taking certain high blood pressure medications
- Age 60 or older
- Taking the medicine for a long period of time
- Harm to fetus (unborn baby)
- Women who want to or can become pregnant
- Pregnant women
- Death from liver failure
- Current liver disease
- Taking with alcohol
- Taking other medicines with acetaminophen
- Death from lack of oxygen to the body (respiratory depression)
- Age 65 or greater
- Higher dose
- People with not enough thyroid hormones
- History of lung problems
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Age 65 or greater
- Tolerance and dependence
- Taking more than the prescribed dose
- Long-term use
- History of drug abuse
- Neonatal withdrawal syndrome
- Long-term use of opioids in mother
- Breastfeeding while taking Percocet (Oxycodone / Acetaminophen)
- Death from overdose (extended-release tablet)
- Children age 18 and younger
- Taking more than prescribed dose
- Mixing with alcohol or drugs that interact with Percocet (Oxycodone / Acetaminophen)
- Severe allergic reactions
- Low blood pressure
- Age 65 years or older
- Circulation problems