Compare Invega vs. Saphris
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps control your thoughts and mood.
Invega (paliperidone) relieves psychotic symptoms and improves mood.
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3.1/ 5 average rating with 34 reviewsforInvega
Treats bipolar disorder and schizophrenia.
While Saphris (asenapine) has fewer side effects compared with other medicines that treat bipolar disorder and schizophrenia, it can be more expensive.
Upsides
- Won't make you as sleepy as other antipsychotic medicines.
- If you have heart or kidney problems, this may be a better option than other antipsychotic medicines.
- The pill and injection form allows for flexible dosing schedule.
- Saphris (asenapine) can be used to treat bipolar disorder in children age 10 or older, and schizophrenia in children age 12 or older.
- You don't need water to take Saphris (asenapine); the pill dissolves in your mouth right away.
- Compared to other medicines, the side effects of Saphris (asenapine) are milder.
Downsides
- Side-effects of weight gain and hormonal imbalance may be intolerable for younger patients.
- Frequent blood tests are sometimes required to check how the medicine is affecting your body.
- Saphris (asenapine) is only available as a brand name.
- Compared to other medicines, Saphris (asenapine) can cause changes in your hormones and make you sleepy.
- You have to take Saphris (asenapine) twice a day, which can be hard to remember.
Used for
Dosage forms
- Pill
- Injection
- Dissolving pill
Price
Lowest price
$112.14
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$599.20
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Reviews
34 reviews so far
29%
saidit'sworth it
32%
saiditworked well
35%
saidit'sa big hassle
Have you used Invega (paliperidone)?
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Side effects
16possible side effects
- Difficulty controlling movements12%
- Drowsiness8%
- Indigestion6%
- Inability to be still6%
- Nausea5%
- Constipation4%
- Weight gain4%
- Abdominal discomfort3%
- Common cold3%
- Back pain3%
- Fast heartbeat2%
- Stomach upset2%
- Upper respiratory tract infection2%
- Decreased appetite2%
- Increased appetite2%
- Changes in speech2%
10possible side effects
- Sleepiness22%
- Trouble sleeping10%
- Difficulty controlling movements6%
- Numbness in the mouth5%
- Fatigue4%
- Dizziness4%
- Indigestion3%
- Swelling in the arms and legs3%
- Weight gain3%
- High blood pressure3%
Risks and risk factors
- Increased risk of death
- Elderly patients with dementia
- Heart problems
- History of heart problems
- Drug interactions
- Shaking and restlessness
- Higher blood sugar and cholesterol and weight gain
- Diabetes
- High cholesterol
- Difficulty concentrating
- Alcohol
- Taking other medicines that make you less alert
- Low blood pressure
- Higher risk of death
- People age 65 or older with dementia and psychosis
- Neuroleptic malignant syndrome
- Taking antipsychotic medications
- Difficulty controlling movements
- Weight gain and diabetes
- Changes in blood pressure and fainting
- High blood pressure
- History of heart disease
- Higher risk of infection