Compare Invokamet vs. Actos
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Invokamet (canagliflozin / metformin) is a combination of 2 medicines that can lower your blood sugars, but it still has to be taken twice daily.
Lowers blood sugar.
Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.
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3.1/ 5 average rating with 175 reviewsforActos
Upsides
- Combines 2 effective anti-diabetes medicines into one pill so you don't have to take them separately.
- Does not cause weight gain unlike other anti-diabetic medicines.
- Not as likely to cause hypoglycemia (low blood sugar)
- Improves sugar control and lowers A1c levels by around 1%.
- Easily taken by mouth as a once a day pill.
- Prevents the harmful effects of high sugar levels on your organs.
- Rarely causes low blood sugar.
- Lower the risk of heart attack or stroke.
Downsides
- Not a good option if you have worsening kidney function such as those age 65 years and up.
- May cause increased urination.
- More likely to cause broken bones and yeast and urinary tract infections.
- May take several weeks to lower blood sugar.
- Can cause weight gain.
- People with heart failure or history of bladder cancer shouldn't use this medicine.
- Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
- Raises the risk of bone fractures, especially for people who already have a risk for fractures.
Used for
- Type 2 diabetes
- Prediabetes
- Diabetic nephropathy
- Atherosclerosis
- Polycystic ovarian syndrome
Dosage forms
- Pill
- Pill
Price
Lowest price
$497.77
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$9.00
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Reviews
Not enough review data.Leave a review
175 reviews so far
42%
saidit'sworth it
30%
saiditworked well
21%
saidit'sa big hassle
Have you used Actos (pioglitazone)?
Leave a reviewSide effects
9possible side effects
- Yeast infection in women11%
- Urinary tract infections6%
- Increased urination5%
- Yeast infection in men4%
- Thirst3%
- Vaginal itching2%
- Constipation2%
- Nausea2%
- Abdominal pain2%
11possible side effects
- Low blood sugar27%
- Swelling27%
- Colds and flu13%
- Headache9%
- Heart failure8%
- Sinus infection6%
- Back pain6%
- Pain in arms and legs6%
- Muscle pain5%
- Sore throat5%
- Chest pain5%
Risks and risk factors
- Acid buildup in the blood
- Kidney problems
- Liver problems
- Congestive heart failure
- Contrast dye for procedure
- Surgery
- Alcohol use
- Low blood pressure (hypotension)
- Over age 65
- Kidney problems
- Diuretics
- Taking ACE inhibitors or ARBs
- Low blood pressure
- Bone fractures
- Low blood pressure
- Weak bones (Osteoporosis)
- Kidney damage
- History of kidney damage
- Heart failure
- Blood pressure medicines (water pills, ACE inhibitors, ACE inhibitors)
- Anti-inflammatories (NSAIDs)
- Genital yeast infection and urinary tract infection
- History of urinary tract infections
- History of fungal genital infections
- Uncircumcised males
- Low blood sugars
- Taking other diabetic medications
- Increased exercise
- Drinking alcohol
- Heart failure
- Heart failure
- Fluid buildup
- Liver damage
- Current liver problems
- Bladder cancer
- History of bladder cancer
- Bone fracture
- Women
- Low blood sugar