Compare Invokamet vs. Precose

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers blood sugar.

Invokamet (canagliflozin / metformin) is a combination of 2 medicines that can lower your blood sugars, but it still has to be taken twice daily.

Lowers blood sugar.

Precose (acarbose) helps lower your post-mealtime blood sugar levels, but it must be taken at the beginning of each main meal in order for it to be most effective.

Upsides
  • Combines 2 effective anti-diabetes medicines into one pill so you don't have to take them separately.
  • Does not cause weight gain unlike other anti-diabetic medicines.
  • Not as likely to cause hypoglycemia (low blood sugar)
  • Precose (acarbose) helps control meal-time blood sugar levels without causing weight gain.
  • When used alone it doesn't normally cause blood sugar levels to be too low unlike other anti-diabetes medicines.
  • Safe to be used in people age 65 or older.
  • Has relatively few interactions with other medicines.
Downsides
  • Not a good option if you have worsening kidney function such as those age 65 years and up.
  • May cause increased urination.
  • More likely to cause broken bones and yeast and urinary tract infections.
  • Not a first choice medicine because it isn't as effective at lowering blood sugar compared to other treatment options.
  • Associated with bothersome side effects like excessive gas and diarrhea.
  • Relatively more expensive than other diabetes medicines.
  • Has to be taken three times a day with each meal.
  • Might cause episodes of low blood sugar when taken together with insulin or medicines that stimulate insulin release.
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Dosage forms
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Reviews
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Side effects
9possible side effects
  • Yeast infection in women
    11%
  • Urinary tract infections
    6%
  • Increased urination
    5%
  • Yeast infection in men
    4%
  • Thirst
    3%
  • Vaginal itching
    2%
  • Constipation
    2%
  • Nausea
    2%
  • Abdominal pain
    2%
See more detailed side effects
3possible side effects
  • Excessive gas
    74%
  • Diarrhea
    31%
  • Stomach pain
    19%
See more detailed side effects
Risks and risk factors
  • Acid buildup in the blood
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Contrast dye for procedure
    • Surgery
    • Alcohol use
  • Low blood pressure (hypotension)
    • Over age 65
    • Kidney problems
    • Diuretics
    • Taking ACE inhibitors or ARBs
    • Low blood pressure
  • Bone fractures
    • Low blood pressure
    • Weak bones (Osteoporosis)
  • Kidney damage
    • History of kidney damage
    • Heart failure
    • Blood pressure medicines (water pills, ACE inhibitors, ACE inhibitors)
    • Anti-inflammatories (NSAIDs)
  • Genital yeast infection and urinary tract infection
    • History of urinary tract infections
    • History of fungal genital infections
    • Uncircumcised males
  • Low blood sugars
    • Taking other diabetic medications
    • Increased exercise
    • Drinking alcohol
See more detailed risks and warnings
  • Low blood sugar
    • Using insulin or other medicines that stimulate insulin release
  • Kidney function
    • Those with kidney problems
  • Interactions with other medicines
    • Taking multiple medicines together
See more detailed risks and warnings