Compare Janumet vs. Novolog

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers your blood sugar.

Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.

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3.4/ 5 average rating with 79 reviewsforJanumet
Lowers blood sugar.

Novolog (insulin aspart) is a fast-acting insulin that provides meal-time blood sugar control. For long-term control, you'll need to take Novolog (insulin aspart) with other medicines to keep your overall blood sugar down.

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3.5/ 5 average rating with 177 reviewsforNovolog
Upsides
  • This 2-in-1 combination can lower the number of pills you have to take daily.
  • Lowers A1c (average blood sugar over time) up to 2.5%.
  • Available in extended and immediate release forms to allow better control of your blood sugar.
  • Doesn't increase your appetite unlike other anti-diabetic medicines.
  • Does not cause hypoglycemia or very low blood sugar.
  • When used correctly, this medication will l lower blood sugar every time you use it and prevent the harmful, long-term effects of high sugar levels on your organs and blood vessels.
  • You can easily change the dose of Novolog (insulin aspart) to fit your individual needs.
  • Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression.
  • Can use Novolog (insulin aspart) even if you have liver or kidney problems, unlike many other blood sugar-lowering medicines.
Downsides
  • Available as brand name only and may be expensive.
  • Metformin component usually causes upset stomach.
  • Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
  • Not appropriate for those with poor kidney function.
  • Have to take insulin by injection.
  • Might have to check your blood sugar multiple times a day, usually before each meal.
  • Novolog (insulin aspart) is likely to cause moderate weight gain.
  • Higher risk of low blood sugar episodes compared to other kinds of diabetes medications.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Injection
Price
Lowest price
$558.80
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Lowest price
$72.88
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Reviews
79 reviews so far
46%
saidit'sworth it
38%
saiditworked well
15%
saidit'sa big hassle

Have you used Janumet (sitagliptin / metformin)?

Leave a review
177 reviews so far
58%
saidit'sworth it
46%
saiditworked well
19%
saidit'sa big hassle

Have you used Novolog (insulin aspart)?

Leave a review
Side effects
5possible side effects
  • Low blood sugar
    16%
  • Diarrhea
    8%
  • Upper respiratory tract infection
    6%
  • Headache
    6%
  • Abdominal pain
    2%
See more detailed side effects
The Novolog (insulin aspart) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Excess lactic acid in the blood
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    • Alcohol use
  • Low vitamin B12 levels
  • Inflammation of the pancreas
  • Serious allergic reactions
See more detailed risks and warnings
  • Life-threatening low blood sugar (Hypoglycemia)
    • Insulin dose too high
    • Use of other blood sugar lowering medicines
    • Poor injection techniques
    • Changes in meal pattern or exercise
    • Kidney problems
    • Liver problems
  • Complications due to low potassium
    • Use of medications that lower potassium
    • Current imbalance of electrolytes
  • Severe allergic reactions
    • Allergy to insulin
See more detailed risks and warnings
Learn more about Janumet (sitagliptin / metformin)
Learn more about Novolog (insulin aspart)