Compare Janumet vs. Prandin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers your blood sugar.

Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.

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3.4/ 5 average rating with 79 reviewsforJanumet
Lowers blood sugar.

Prandin (repaglinide) works quickly to lower blood sugar, especially during mealtimes. However, it can cause hypoglycemia (low blood sugar) if you are not consistent with your diet and exercise schedule.

Upsides
  • This 2-in-1 combination can lower the number of pills you have to take daily.
  • Lowers A1c (average blood sugar over time) up to 2.5%.
  • Available in extended and immediate release forms to allow better control of your blood sugar.
  • Doesn't increase your appetite unlike other anti-diabetic medicines.
  • Does not cause hypoglycemia or very low blood sugar.
  • Quickly and effectively lowers blood sugar during meal times.
  • Less likely to cause hypoglycemia (low blood sugar) than Starlix (nateglinide).
  • Good first-choice if you cannot tolerate metformin or add-on therapy if your blood sugars are not controlled on metformin alone.
Downsides
  • Available as brand name only and may be expensive.
  • Metformin component usually causes upset stomach.
  • Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
  • Not appropriate for those with poor kidney function.
  • May cause some weight gain.
  • May cause hypoglycemia (low blood sugar).
  • Can frequently interfere with how other medicines work.
  • Not a good choice if you have poor kidney function, liver problems, or younger than 18 years old.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
Lowest price
$511.29
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Lowest price
$32.65
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Reviews
79 reviews so far
46%
saidit'sworth it
38%
saiditworked well
15%
saidit'sa big hassle

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Side effects
5possible side effects
  • Low blood sugar
    16%
  • Diarrhea
    8%
  • Upper respiratory tract infection
    6%
  • Headache
    6%
  • Abdominal pain
    2%
See more detailed side effects
20possible side effects
  • Low blood sugar
    31%
  • Headache
    11%
  • Sinusitis
    6%
  • Joint pain
    6%
  • Nausea
    5%
  • Diarrhea
    5%
  • Back pain
    5%
  • Swelling in arms and legs
    5%
  • Heart failure
    4%
  • Rhinitis
    3%
  • Constipation
    3%
  • Vomiting
    3%
  • Tingling, numbness, or burning sensation on the skin
    3%
  • Chest pain
    3%
  • Weight gain
    3%
  • Inflammation of the airways
    2%
  • Indigestion
    2%
  • Urinary tract infection
    2%
  • Tooth disorder
    2%
  • Allergy
    2%
See more detailed side effects
Risks and risk factors
  • Excess lactic acid in the blood
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    • Alcohol use
  • Low vitamin B12 levels
  • Inflammation of the pancreas
  • Serious allergic reactions
See more detailed risks and warnings
  • Low blood sugar (hypoglycemia)
    • Alcoholism
    • Changes in meal pattern
    • Changes in exercise
    • Insulin
    • Other antidiabetic medications
    • Elderly
    • Bad liver or kidney function
  • Heart damage
    • use with NPH-insulin
See more detailed risks and warnings
Learn more about Janumet (sitagliptin / metformin)
Learn more about Prandin (repaglinide)