Compare Janumet vs. Starlix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lowers your blood sugar.

Janumet is a combination of two anti-diabetic medicines that work better together, but is available as brand only.

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3.4/ 5 average rating with 79 reviewsforJanumet
Lowers blood sugar.

Starlix (nateglinide) can quickly lower your blood sugar, but needs to be timed with your meals.

Upsides
  • This 2-in-1 combination can lower the number of pills you have to take daily.
  • Lowers A1c (average blood sugar over time) up to 2.5%.
  • Available in extended and immediate release forms to allow better control of your blood sugar.
  • Doesn't increase your appetite unlike other anti-diabetic medicines.
  • Does not cause hypoglycemia or very low blood sugar.
  • Can quickly lower blood sugar.
  • Good alternative if you have poor kidney function.
  • Can be safely used in people 65 and older.
  • Widely available in generic (cheaper) form.
Downsides
  • Available as brand name only and may be expensive.
  • Metformin component usually causes upset stomach.
  • Sitagliptin component may increase your risk for throat infections and inflammation of pancreas.
  • Not appropriate for those with poor kidney function.
  • Take during mealtime.
  • May need to take as often as three times daily.
  • Can easily cause hypoglycemia (low blood sugar) if you don't maintain a consistent diet or exercise schedule.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
Lowest price
$511.29
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Lowest price
$27.72
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Reviews
79 reviews so far
46%
saidit'sworth it
38%
saiditworked well
15%
saidit'sa big hassle

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Side effects
5possible side effects
  • Low blood sugar
    16%
  • Diarrhea
    8%
  • Upper respiratory tract infection
    6%
  • Headache
    6%
  • Abdominal pain
    2%
See more detailed side effects
10possible side effects
  • Common cold
    11%
  • Back pain
    4%
  • Flu symptoms
    4%
  • Dizziness
    4%
  • Joint problems
    3%
  • Diarrhea
    3%
  • Accidental trauma
    3%
  • Inflammation of the airways
    3%
  • Coughing
    2%
  • Low blood sugar
    2%
See more detailed side effects
Risks and risk factors
  • Excess lactic acid in the blood
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    • Alcohol use
  • Low vitamin B12 levels
  • Inflammation of the pancreas
  • Serious allergic reactions
See more detailed risks and warnings
  • Low blood sugar (hypoglycemia)
    • Changes in meal pattern
    • Changes in how much exercise you do
    • Taking other antidiabetic medications
    • Bad liver or renal function
See more detailed risks and warnings
Learn more about Janumet (sitagliptin / metformin)
Learn more about Starlix (nateglinide)