Compare Januvia vs. Glucovance
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers your blood sugar.
Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.
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3.2/ 5 average rating with 143 reviewsforJanuvia
Lowers blood sugar.
Glyburide / Metformin is an effective combination medicine for lowering blood sugar, but it is likely to cause diarrhea in the first few weeks.
Upsides
- Oral blood sugar-lowering medicine.
- Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
- Uses the hormones naturally produced by your body to affect how sugar is processed.
- It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
- Glyburide / Metformin effectively lowers blood sugar levels more so than if each of the individual medicines it contains are taken alone.
- Protects your organs and blood vessels from the harmful effects of high blood sugar levels.
- Can potentially lower your "bad cholesterol" levels.
- Glyburide / Metformin is available in a generic form and is cheaper than many other combination diabetes medicines.
Downsides
- Lowers A1c (average blood sugar over time) by less than 1%.
- Available as brand version only.
- Some people might get frequent cold-like symptoms.
- Rare but serious side effects include pancreatitis and severe joint pain.
- Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
- Glyburide / Metformin is likely to cause nausea, stomach upset, or diarrhea in the first few weeks.
- Not a good treatment option for those with kidney and/or liver problems.
- Drinking large amounts of or frequently using alcohol while taking Glyburide / Metformin can cause harm to your body.
- Can cause some weight gain.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$465.18
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$14.28
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Reviews
143 reviews so far
44%
saidit'sworth it
34%
saiditworked well
17%
saidit'sa big hassle
Have you used Januvia (sitagliptin)?
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Side effects
6possible side effects
- Upper respiratory infection17%
- Diarrhea17%
- Headache9%
- Nausea/vomiting8%
- Stomach pain7%
- Dizziness6%
Risks and risk factors
- Death from inflammation of the pancreas (pancreatitis)
- History of pancreatitis
- High blood triglyceride levels
- Gallstones (stones in gallbladder)
- History of alchoholism
- Kidney problems
- Serious allergic reactions
- Kidney damage
- Pre-existing kidney damage
- Low blood sugar (hypoglycemia)
- Taking medicines for diabetes
- Severe joint pain and swelling
- Lactic acid build up in blood
- History of kidney problems
- History of liver problems
- Those with congestive heart failure
- Using contrast dye for procedures
- Undergoing surgery
- Drinking large amounts or frequent use of alcohol
- Serious heart problems
- Low blood sugar
- Skipping meals or having inconsistent meal times
- Drinking alcohol
- Using other blood sugar-lowering medicine
- People age 60 or older
- Those with kidney and/or liver problems
- Severe allergic reaction
- History of allergy to sulfa-containing medicine
- Breakdown of red blood cells
- People with G6PD deficiency