Compare Januvia vs. Humalog
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.
Humalog (insulin lispro) is a fast-acting insulin that controls blood sugar around meal times.
- Oral blood sugar-lowering medicine.
- Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
- Uses the hormones naturally produced by your body to affect how sugar is processed.
- It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
- Humalog (insulin lispro) is the most effective medication for lowering your blood sugar.
- Works quickly to control your sugar levels after meals.
- Dose can be easily adjusted to create a regimen that's tailored to your body's needs.
- Humalog (insulin lispro) can be used even if you have liver or kidney problems, unlike other anti-diabetic medications.
- Lowers A1c (average blood sugar over time) by less than 1%.
- Available as brand version only.
- Some people might get frequent cold-like symptoms.
- Rare but serious side effects include pancreatitis and severe joint pain.
- You have to take Humalog (insulin lispro) by injection.
- Humalog (insulin lispro) is likely to cause moderate weight gain (around 4 to 6 pounds).
- There is a higher risk for episodes of low blood sugar compared to other anti-diabetic medications.
- Effects do not last long enough to control your blood sugar for a whole day.
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- Common cold5%
- Abdominal pain2%
- Death from inflammation of the pancreas (pancreatitis)
- History of pancreatitis
- High blood triglyceride levels
- Gallstones (stones in gallbladder)
- History of alchoholism
- Kidney problems
- Serious allergic reactions
- Kidney damage
- Pre-existing kidney damage
- Low blood sugar (hypoglycemia)
- Taking medicines for diabetes
- Severe joint pain and swelling
- Life-threatening low blood sugar (hypoglycemia)
- Insulin dose too high
- Use of other blood sugar lowering medications
- Poor injection techniques
- Complications due to low potassium
- Use of medications that lower potassium
- Current electrolyte imbalance
- Severe allergic reactions
- Allergy to insulin