Compare Januvia vs. Human Insulin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Januvia (sitagliptin) is a good add-on treatment if your blood sugars are not controlled and you don't want to use an injectable medicine.
This form of insulin is one of the few medications in its class that you can get without a prescription, but it's expensive.
- Oral blood sugar-lowering medicine.
- Januvia (sitagliptin) is not linked to worsening heart failure like other medicines in its class.
- Uses the hormones naturally produced by your body to affect how sugar is processed.
- It is less likely to cause weight gain and low blood sugar compared to other diabetes medicines.
- Some types of this medication are available without a prescription.
- Available as a shot to be injected into the fatty part of the skin, and as a powder to be inhaled through your nose.
- Available in different combinations so that you can do one shot or multiple shots a day.
- Lowers A1c (average blood sugar over time) by less than 1%.
- Available as brand version only.
- Some people might get frequent cold-like symptoms.
- Rare but serious side effects include pancreatitis and severe joint pain.
- Has to be taken exactly as directed or it can cause high or low blood sugar.
- As with all insulins, you have to work with your doctor closely to make sure you're giving yourself the correct dose, or you can have low or high blood sugar.
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- Common cold5%
- Abdominal pain2%
- Death from inflammation of the pancreas (pancreatitis)
- History of pancreatitis
- High blood triglyceride levels
- Gallstones (stones in gallbladder)
- History of alchoholism
- Kidney problems
- Serious allergic reactions
- Kidney damage
- Pre-existing kidney damage
- Low blood sugar (hypoglycemia)
- Taking medicines for diabetes
- Severe joint pain and swelling
- Changes in blood sugar
- Changes in skin appearance
- Weight gain