Compare Jardiance vs. Actos
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Jardiance (empagliflozin) lowers blood sugar for people with diabetes, but can increase the chance of a yeast infection.
Lowers blood sugar.
Actos (pioglitazone) can improve blood sugar control but is not a top choice since it has a lot of side effects.
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3.1/ 5 average rating with 175 reviewsforActos
Upsides
- Lowers A1c (average blood sugar over time) levels up to 1%.
- Can prevent death from heart attack, stroke, or heart failure if you have pre-existing heart disease.
- Can be easily taken orally as a pill.
- Can cause weight loss.
- Not likely to cause hypoglycemia or very low blood sugar.
- Improves sugar control and lowers A1c levels by around 1%.
- Easily taken by mouth as a once a day pill.
- Prevents the harmful effects of high sugar levels on your organs.
- Rarely causes low blood sugar.
- Lower the risk of heart attack or stroke.
Downsides
- More expensive since it's available as brand name only.
- Can cause dehydration.
- May take several weeks to lower blood sugar.
- Can cause weight gain.
- People with heart failure or history of bladder cancer shouldn't use this medicine.
- Some people might get fluid accumulation (edema), from minor ankle swelling to fluid in lungs that makes it hard to breathe.
- Raises the risk of bone fractures, especially for people who already have a risk for fractures.
Used for
- Type 2 diabetes
- Prediabetes
- Diabetic nephropathy
- Atherosclerosis
- Polycystic ovarian syndrome
Dosage forms
- Pill
- Pill
Price
Lowest price
$578.51
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$14.62
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Reviews
Not enough review data.Leave a review
175 reviews so far
42%
saidit'sworth it
30%
saiditworked well
21%
saidit'sa big hassle
Have you used Actos (pioglitazone)?
Leave a reviewSide effects
9possible side effects
- Low blood sugar40%
- Urinary tract infection9%
- Yeast infection in women5%
- Elevated cholesterol levels4%
- Head cold3%
- Increased urination3%
- Yeast infection in men3%
- Joint pain2%
- Nausea2%
11possible side effects
- Low blood sugar27%
- Swelling27%
- Colds and flu13%
- Headache9%
- Heart failure8%
- Sinus infection6%
- Back pain6%
- Pain in arms and legs6%
- Muscle pain5%
- Sore throat5%
- Chest pain5%
Risks and risk factors
- Low blood pressure
- Over age 65
- Kidney disease
- Taking blood pressure medications
- Worsening kidney function
- Dehydration
- Poor baseline kidney function
- Congestive heart failure
- Too much acid in the blood
- Type 1 diabetes
- Extended fasting
- Yeast infections and urinary tract infections
- Heart failure
- Heart failure
- Fluid buildup
- Liver damage
- Current liver problems
- Bladder cancer
- History of bladder cancer
- Bone fracture
- Women
- Low blood sugar