Compare Jardiance vs. Glucovance
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Jardiance (empagliflozin) lowers blood sugar for people with diabetes, but can increase the chance of a yeast infection.
Lowers blood sugar.
Glyburide / Metformin is an effective combination medicine for lowering blood sugar, but it is likely to cause diarrhea in the first few weeks.
Upsides
- Lowers A1c (average blood sugar over time) levels up to 1%.
- Can prevent death from heart attack, stroke, or heart failure if you have pre-existing heart disease.
- Can be easily taken orally as a pill.
- Can cause weight loss.
- Not likely to cause hypoglycemia or very low blood sugar.
- Glyburide / Metformin effectively lowers blood sugar levels more so than if each of the individual medicines it contains are taken alone.
- Protects your organs and blood vessels from the harmful effects of high blood sugar levels.
- Can potentially lower your "bad cholesterol" levels.
- Glyburide / Metformin is available in a generic form and is cheaper than many other combination diabetes medicines.
Downsides
- More expensive since it's available as brand name only.
- Can cause dehydration.
- Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
- Glyburide / Metformin is likely to cause nausea, stomach upset, or diarrhea in the first few weeks.
- Not a good treatment option for those with kidney and/or liver problems.
- Drinking large amounts of or frequently using alcohol while taking Glyburide / Metformin can cause harm to your body.
- Can cause some weight gain.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$529.30
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$25.50
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Side effects
9possible side effects
- Low blood sugar40%
- Urinary tract infection9%
- Yeast infection in women5%
- Elevated cholesterol levels4%
- Head cold3%
- Increased urination3%
- Yeast infection in men3%
- Joint pain2%
- Nausea2%
6possible side effects
- Upper respiratory infection17%
- Diarrhea17%
- Headache9%
- Nausea/vomiting8%
- Stomach pain7%
- Dizziness6%
Risks and risk factors
- Low blood pressure
- Over age 65
- Kidney disease
- Taking blood pressure medications
- Worsening kidney function
- Dehydration
- Poor baseline kidney function
- Congestive heart failure
- Too much acid in the blood
- Type 1 diabetes
- Extended fasting
- Yeast infections and urinary tract infections
- Lactic acid build up in blood
- History of kidney problems
- History of liver problems
- Those with congestive heart failure
- Using contrast dye for procedures
- Undergoing surgery
- Drinking large amounts or frequent use of alcohol
- Serious heart problems
- Low blood sugar
- Skipping meals or having inconsistent meal times
- Drinking alcohol
- Using other blood sugar-lowering medicine
- People age 60 or older
- Those with kidney and/or liver problems
- Severe allergic reaction
- History of allergy to sulfa-containing medicine
- Breakdown of red blood cells
- People with G6PD deficiency